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Mother Machine chip

Microfluidic mother machine chip is an advanced biochip technology that integrates microfluidics and cell biology, aiming to simulate and study various stages of mother cells in the cell cycle and related molecular and biological processes. This technology utilizes microstructures such as microchannels, microreactors, and microvalves for highly precise manipulation and observation of mother cells at the microscopic scale. The following is a detailed overview of the mother machine chip, covering its principles, applications, advantages, and potential impact on cell biology and medical research.

Plant microfluidic chips

Plant microfluidic chips are increasingly important tools in the field of plant science, with applications spanning plant growth, plant physiology, and plant stress responses. These chips leverage microfluidic technology to finely control and analyze plants through microchannels and microreactors, providing a novel approach to studying plant growth and development, metabolic processes, and plant responses to environmental changes. The following is an overview of plant microfluidic chips, including their principles, applications, advantages, and potential contributions to plant science research.

Lung chip/Lung on a chip

The microfluidic lung chip/lung on a chip is a miniature experimental platform designed and manufactured based on microfluidics technology to simulate the structure and function of the lungs. It consists of a series of microchannels, chambers, and cell culture membranes, creating a micro-organ that can replicate physiological and pathological processes such as respiratory movements, oxygen and carbon dioxide exchange, and immune responses in the lungs. By introducing different types of cells, viruses, bacteria, and drugs into the chip, it is possible to simulate lung diseases and conduct drug screening.

Engineered Heart Tissue Chips

Heart disease has consistently been a major global health concern, and the research and screening of drugs are crucial for treating these conditions. In recent years, an innovative technology called Engineered Heart Tissue Chips (organ on a chip, microfluidic chips) has garnered widespread attention. This technology utilizes Engineered Heart Tissue (EHT) to create a unique drug screening platform, simulating the three-dimensional structure and mechanical responsiveness of real heart tissue, providing researchers with a more realistic and controllable experimental environment. This article will delve into the key features, advantages, and potential applications of Engineered Heart Tissue Chips in the development of cardiac tissue and the pharmaceutical research field.

Microfluidic PEEK Chips/Cell Culture Chips

Many in vitro methods have long been used for high-throughput drug screening or toxicology testing. However, most of the currently available systems are only partial approximations of human biology and therefore have limited predictive power. Indeed, these systems are either based on human cell cultures, which are unable to capture the complexity of cell behavior in a three-dimensional (3D) environment, or on animal tissue fragments, which have...

organoid chip

An advanced organoid chip technology inspired by the concept of organoid chips, it consists of two independent channels that support 2D and 3D cell cultures to mimic physiological environments, especially in studying the effects of fluid shear stress on gene expression in blood vessels.

Sperm sorting chip

Sperm sorting chips are an advanced technological tool designed specifically for reproductive therapy. Their core advantages include efficiently selecting ideal sperm without the need for cumbersome sample preparation, as well as a standardized and streamlined operational process.

Cell Migration Chip

Cell migration refers to the movement of cells in response to migration signals or the detection of concentration gradients of certain substances. During the movement, cells repeatedly extend protrusions or pseudopodia forward, followed by the retraction of the rear cell body in a cyclical process. The material basis for this process includes the cell cytoskeleton, associated proteins, and the cell matrix. Additionally, various substances intricately regulate this process.