Top Asahi provides various microfluidic chips, microfluidic chip processing equipment and microfluidic commonly used consumables, and we also provide professional microfluidic chip customization services.
Lipid Nanoparticle Chip (LNC) is an advanced technology with wide applications in nanotechnology, which is designed based on the special structure of lipid nanoparticles for efficient drug delivery and biomedical research.
微流体技术的不断进步推动了生物芯片领域的发展，其中DLD（Deterministic lateral displacement）分选芯片作为一项创新技术，为细胞分选领域带来了新的可能性。 本文将详细介绍DLD分选芯片的原理、优势、应用领域以及未来发展趋势。 一、细胞分选芯片的原理 DLD分选芯片采用了独特的DLD技术，即位移导向分选技术，其原理基于微小颗粒在微流控通道中的运动行为。 DLD分选芯片的微通道表面设计了一系列微米级的障碍物，这些障碍物能够在微小液体流动中导致颗粒的偏移，从而实现对颗粒的分选。 当细胞通过微通道时，其形态和柔韧性的不同将导致在DLD结构中产生不同的偏移，从而实现对细胞…
Microfluidic Droplet Sequencing Chip is an advanced biochip that combines microfluidic technology and high-throughput sequencing technology. Its core principle is to form tiny droplets within the chip by means of microfluidics, with each droplet being equivalent to a microreaction chamber, enabling large-scale, high-throughput gene sequencing on a single chip.
Microfluidic Lung Organ Chip is a micro experimental platform designed and fabricated based on microfluidics technology to simulate the structure and function of the lungs. It is a micro-organ composed of a series of micro-channels, chambers and cell culture membranes, which can simulate physiological and pathological processes such as respiratory movements, exchange of oxygen and carbon dioxide, and immune responses in the lungs.
PDMS (Polydimethylsiloxane) stamps are crucial tools in micro and nanofabrication, typically prepared using photolithography techniques. In Microcontact Printing, PDMS stamps serve as flexible templates with the capability to efficiently transfer small patterns. Their flexibility and ease of fabrication make them widely applied in the preparation of biochips, biosensors, and microelectronic devices. The development of PDMS stamps has undergone several stages and faced various challenges. Currently, researchers are actively addressing these challenges and exploring broader application areas. This article will elaborate on the developmental stages of PDMS stamps, current challenges, future directions, and application scenarios.
Heart disease has consistently been a major global health concern, and the research and screening of drugs are crucial for treating these conditions. In recent years, an innovative technology called Engineered Heart Tissue Chips (organ on a chip, microfluidic chips) has garnered widespread attention. This technology utilizes Engineered Heart Tissue (EHT) to create a unique drug screening platform, simulating the three-dimensional structure and mechanical responsiveness of real heart tissue, providing researchers with a more realistic and controllable experimental environment. This article will delve into the key features, advantages, and potential applications of Engineered Heart Tissue Chips in the development of cardiac tissue and the pharmaceutical research field.
Many in vitro methods have long been used for high-throughput drug screening or toxicology testing. However, most of the currently available systems are only partial approximations of human biology and therefore have limited predictive power. Indeed, these systems are either based on human cell cultures, which are unable to capture the complexity of cell behavior in a three-dimensional (3D) environment, or on animal tissue fragments, which are 3D in nature but only partially biologically similar to human tissues, and are unable to account for interactions with other organs. To overcome these limitations, a new generation of bioreactors is being developed to generate multiple human cell-based tissue analogs in the same fluidic system to better reproduce the complexity and interconnections of human physiology. These efforts are aimed at creating multi-tissue organ systems (cardiovascular, gastrointestinal, musculoskeletal, etc.) and ultimately connecting them into an interconnected human-on-a-chip device that is capable of realistically recreating the complexity of the human body's response to disease and potential drug treatments.
Microfluidic plastic chips are miniature laboratory devices made from polymer materials, featuring microchannels and microchambers for controlling and analyzing microfluids. In comparison to traditional glass chips, plastic chips offer advantages such as low cost, flexible fabrication, lightweight, and easy processing. Widely applied in biomedical research, chemical analysis, environmental monitoring, etc., these chips enable effective experiments like micro-reactions, cell culture, drug screening, providing convenient tools for laboratory research. Microfluidic plastic chips play a crucial role in advancing microfluidic technology, promoting automation, and high-throughput experiments in laboratories.
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