{"id":5510,"date":"2026-01-06T14:07:57","date_gmt":"2026-01-06T06:07:57","guid":{"rendered":"https:\/\/www.dxfluidics.com\/?p=5510"},"modified":"2026-01-06T14:08:01","modified_gmt":"2026-01-06T06:08:01","slug":"%e5%be%ae%e6%b5%81%e6%8e%a7%e5%ae%9e%e4%bd%93%e7%98%a4%e5%85%8d%e7%96%ab%e6%b2%bb%e7%96%97%e7%a0%94%e7%a9%b6%e4%b8%8e%e4%b8%b4%e5%ba%8a%e8%bd%ac%e5%8c%96%e5%ba%94%e7%94%a8","status":"publish","type":"post","link":"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/5510\/%e5%be%ae%e6%b5%81%e6%8e%a7%e5%ae%9e%e4%bd%93%e7%98%a4%e5%85%8d%e7%96%ab%e6%b2%bb%e7%96%97%e7%a0%94%e7%a9%b6%e4%b8%8e%e4%b8%b4%e5%ba%8a%e8%bd%ac%e5%8c%96%e5%ba%94%e7%94%a8\/","title":{"rendered":"\u5fae\u6d41\u63a7\u6280\u672f\u5b9e\u4f53\u7624\u514d\u75ab\u6cbb\u7597\uff1a\u7814\u7a76\u8fdb\u5c55\u3001\u6838\u5fc3\u5e94\u7528\u4e0e\u6280\u672f\u7a81\u7834"},"content":{"rendered":"

1.    \u5f15\u8a00<\/h2>\n\n\n\n

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2.    \u5b9e\u4f53\u7624\u514d\u75ab\u6cbb\u7597\u7684\u4e3b\u8981\u7b56\u7565\u4e0e\u4e34\u5e8a\u6311\u6218<\/h2>\n\n\n\n

1)    \u6838\u5fc3\u514d\u75ab\u6cbb\u7597\u6280\u672f\u8def\u5f84<\/h3>\n\n\n
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    \n
  1. \u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff08ICIs\uff09\uff1a\u4f5c\u4e3a\u76ee\u524d\u6700\u6210\u529f\u7684\u514d\u75ab\u6cbb\u7597\u7c7b\u578b\uff0c\u901a\u8fc7\u963b\u65ad T \u7ec6\u80de\u8868\u9762 CTLA-4\u3001PD-1 \u7b49\u5171\u6291\u5236\u5206\u5b50\u4e0e\u914d\u4f53\u7684\u7ed3\u5408\uff0c\u89e3\u9664\u514d\u75ab\u6291\u5236\uff0c\u91ca\u653e T \u7ec6\u80de\u6740\u4f24\u6d3b\u6027\u3002PD-1 \u6291\u5236\u5242\u5e15\u535a\u5229\u73e0\u5355\u6297\u3001\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u5df2\u83b7\u6279\u7528\u4e8e 25 \u79cd\u4ee5\u4e0a\u5b9e\u4f53\u7624\u6cbb\u7597\uff0c\u4f46\u5728\u9ed1\u8272\u7d20\u7624\u3001\u80ba\u764c\u4e2d\u7684\u54cd\u5e94\u7387\u4ecd\u4e0d\u8db3 40%\uff0c\u4e9f\u9700\u66f4\u7cbe\u51c6\u7684\u9884\u4e34\u5e8a\u6a21\u578b\u4f18\u5316\u6cbb\u7597\u65b9\u6848\u3002<\/li>\n\n\n\n
  2. \u8fc7\u7ee7\u6027\u7ec6\u80de\u8f6c\u79fb\uff08ACT\uff09\uff1a\u5305\u62ec\u80bf\u7624\u6d78\u6da6 T \u7ec6\u80de\u3001CAR-T \u7ec6\u80de\u3001NK \u7ec6\u80de\u7b49\u514d\u75ab\u7ec6\u80de\u7684\u4f53\u5916\u5206\u79bb\u3001\u4fee\u9970\u4e0e\u6269\u589e\uff0c\u56de\u8f93\u60a3\u8005\u4f53\u5185\u53d1\u6325\u6740\u4f24\u4f5c\u7528\u3002CAR-T \u7ec6\u80de\u5728\u8840\u6db2\u80bf\u7624\u4e2d\u7597\u6548\u663e\u8457\uff0c\u4f46\u5b9e\u4f53\u7624\u6cbb\u7597\u9762\u4e34\u80bf\u7624\u7279\u5f02\u6027\u6297\u539f\u7f3a\u4e4f\u3001TME \u6291\u5236\u7ec6\u80de\u6d78\u6da6\u7b49\u95ee\u9898\uff0c\u800c NK \u7ec6\u80de\u901a\u8fc7\u7ec6\u80de\u5171\u57f9\u517b\u82af\u7247\u7814\u7a76\u663e\u793a\uff0c\u5176\u5728 3D \u73af\u5883\u4e2d\u7684\u7ec6\u80de\u6bd2\u6027\u4e0e 2D \u6a21\u578b\u5b58\u5728\u663e\u8457\u5dee\u5f02\u3002<\/li>\n\n\n\n
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  4. \u7ec6\u80de\u56e0\u5b50\u7597\u6cd5\uff1a\u5e72\u6270\u7d20\u3001\u767d\u4ecb\u7d20\u7b49\u7ec6\u80de\u56e0\u5b50\u53ef\u589e\u5f3a\u514d\u75ab\u7ec6\u80de\u6d3b\u6027\u3001\u8bf1\u5bfc\u764c\u7ec6\u80de\u51cb\u4ea1\uff0c\u4f46\u534a\u8870\u671f\u77ed\u3001\u9ad8\u5242\u91cf\u6613\u5f15\u53d1\u4e25\u91cd\u526f\u4f5c\u7528\uff0c\u5176\u9012\u9001\u6548\u7387\u4e0e\u5b89\u5168\u6027\u9700\u501f\u52a9\u5fae\u6d41\u63a7\u82af\u7247\u8fdb\u884c\u7cbe\u51c6\u8bc4\u4f30\u3002<\/li>\n<\/ol>\n\n\n\n

    2)    \u4e34\u5e8a\u8f6c\u5316\u7684\u6838\u5fc3\u74f6\u9888<\/h3>\n\n\n\n

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    3.    \u5fae\u6d41\u63a7\u6280\u672f\u5728\u5b9e\u4f53\u7624\u514d\u75ab\u6cbb\u7597\u7814\u7a76\u4e2d\u7684\u6838\u5fc3\u5e94\u7528<\/h2>\n\n\n\n

    1)    \u80bf\u7624 – \u514d\u75ab\u7ec6\u80de\u76f8\u4e92\u4f5c\u7528\u4e0e\u8fc1\u79fb\u7814\u7a76<\/h3>\n\n\n\n

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    2)    \u514d\u75ab\u7ec6\u80de\u4ecb\u5bfc\u7684\u7ec6\u80de\u6bd2\u6027\u8bc4\u4f30<\/h3>\n\n\n\n

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    \n
    \"\"<\/figure>\n<\/div>\n\n\n

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    3)    \u514d\u75ab\u6cbb\u7597\u673a\u5236\u4e0e\u8054\u5408\u7597\u6cd5\u7814\u7a76<\/h3>\n\n\n\n

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    \n
    \"\"<\/figure>\n<\/div>\n\n\n

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    \n
    \"\"<\/figure>\n<\/div>\n\n\n

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    \n
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    4.    \u5fae\u6d41\u63a7\u82af\u7247\u5173\u952e\u5236\u5907\u4e0e\u52a0\u5de5\u6280\u672f<\/h2>\n\n\n\n

    1)    \u6838\u5fc3\u6750\u6599\u4e0e\u52a0\u5de5\u5de5\u827a<\/h3>\n\n\n\n

    \u5fae\u6d41\u63a7\u82af\u7247\u7684\u6027\u80fd\u4f9d\u8d56\u4e8e\u6750\u6599\u9009\u62e9\u4e0e\u52a0\u5de5\u7cbe\u5ea6\u3002PDMS \u56e0\u751f\u7269\u76f8\u5bb9\u6027\u3001\u5149\u5b66\u900f\u660e\u5ea6\u4e0e\u6c14\u4f53\u901a\u900f\u6027\uff0c\u6210\u4e3a 80% \u4ee5\u4e0a\u7814\u7a76\u7684\u9996\u9009\u6750\u6599\uff0c\u5176\u5236\u5907\u8fc7\u7a0b\u6d89\u53ca PDMS \u6d47\u7b51\u3001\u5149\u523b\u80f6\u6a21\u5177\uff08\u5982 SU8 \u6a21\u5177\uff09\u6210\u578b\u3001PDMS \u7b49\u79bb\u5b50\u952e\u5408\u7b49\u5173\u952e\u6b65\u9aa4\u3002MEMS \u52a0\u5de5\u6280\u672f\uff08\u5982\u7535\u5b50\u675f\u5149\u523b\u3001\u6df1\u7845\u523b\u8680\u3001\u9633\u6781\u952e\u5408\uff09\u7528\u4e8e\u5236\u4f5c\u9ad8\u7cbe\u5ea6\u5fae\u901a\u9053\u4e0e\u5fae\u53cd\u5e94\u5668\uff0c\u800c\u6ce8\u5851\u6210\u578b\u5de5\u827a\u5219\u652f\u6301\u805a\u82ef\u4e59\u70ef\u3001COP \u7b49\u6750\u6599\u82af\u7247\u7684\u6279\u91cf\u751f\u4ea7\uff0c\u6ee1\u8db3\u9ad8\u901a\u91cf\u7814\u7a76\u9700\u6c42\u3002<\/p>\n\n\n\n

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    2)    \u82af\u7247\u7c7b\u578b\u4e0e\u529f\u80fd\u62d3\u5c55<\/h3>\n\n\n\n

    \u6839\u636e\u5e94\u7528\u573a\u666f\uff0c\u5fae\u6d41\u63a7\u82af\u7247\u53ef\u5206\u4e3a\u7ec6\u80de\u5171\u57f9\u517b\u82af\u7247\u3001\u6d53\u5ea6\u68af\u5ea6\u82af\u7247\u3001\u5668\u5b98\u82af\u7247\uff08\u5982 liver-chip\u3001brain-chip\uff09\u7b49\u30023D \u7ec6\u80de\u57f9\u517b\u82af\u7247\u901a\u8fc7 hydrogel \u5d4c\u5165\u3001\u80bf\u7624\u7403\u57f9\u517b\u7b49\u65b9\u5f0f\uff0c\u6a21\u62df\u5b9e\u4f53\u7624\u7684\u7a7a\u95f4\u7ed3\u6784\uff1b\u800c\u591a\u5668\u5b98\u82af\u7247\uff08\u5982\u8840\u7ba1 – \u80bf\u7624 – \u514d\u75ab\u5668\u5b98\u96c6\u6210\u82af\u7247\uff09\u5219\u53ef\u8bc4\u4f30\u514d\u75ab\u6cbb\u7597\u7684\u7cfb\u7edf\u6027\u6548\u5e94\u3002\u5728\u4e2a\u6027\u5316\u533b\u7597\u4e2d\uff0c\u60a3\u8005\u6d3b\u68c0\u7ec4\u7ec7\u5fae\u6d41\u63a7\u82af\u7247\u53ef\u540c\u65f6\u6d4b\u8bd5\u591a\u79cd\u514d\u75ab\u7597\u6cd5\uff08\u5982 ICB\u3001CAR-T\u3001\u75ab\u82d7\uff09\uff0c\u5b9e\u73b0\u6cbb\u7597\u65b9\u6848\u7684\u7cbe\u51c6\u7b5b\u9009\u3002<\/p>\n\n\n\n

    \u5fae\u6d41\u63a7\u82af\u7247\u7684\u529f\u80fd\u62d3\u5c55\u8fd8\u4f9d\u8d56\u4e8e\u96c6\u6210\u5316\u8bbe\u8ba1\uff0c\u5982\u5c06\u5fae\u6d41\u63a7\u4e0e PCR \u6280\u672f\u7ed3\u5408\u7684\u6570\u5b57 PCR \u82af\u7247\u3001\u6574\u5408\u4f20\u611f\u5668\u7684\u5b9e\u65f6\u76d1\u6d4b\u82af\u7247\uff0c\u4ee5\u53ca\u4e0e\u7eb3\u7c73\u6280\u672f\u7ed3\u5408\u7684\u836f\u7269\u9012\u9001\u82af\u7247\uff08\u5982\u53f6\u9178\u4fee\u9970\u7eb3\u7c73\u9897\u7c92\u9776\u5411\u9012\u9001 chemokine\uff09\u3002\u8fd9\u4e9b\u521b\u65b0\u5747\u57fa\u4e8e\u5fae\u7eb3\u52a0\u5de5\u5e73\u53f0\u7684\u6280\u672f\u7a81\u7834\uff0c\u5982\u5fae\u6d41\u63a7\u4e0e MEMS \u7684\u96c6\u6210\u3001\u6fc0\u5149\u5de5\u7a0b\u7845\u5fae\u6a21\u5177\u7684\u9ad8\u7cbe\u5ea6\u5236\u9020\u3002<\/p>\n\n\n\n

    5.    \u6311\u6218\u4e0e\u672a\u6765\u5c55\u671b<\/h2>\n\n\n\n

    1)    \u5f53\u524d\u6280\u672f\u74f6\u9888<\/h3>\n\n\n\n

    \u5fae\u6d41\u63a7\u6280\u672f\u7684\u5e7f\u6cdb\u5e94\u7528\u4ecd\u9762\u4e34\u591a\u91cd\u6311\u6218\uff1a\u6750\u6599\u65b9\u9762\uff0cPDMS \u7684\u836f\u7269\u5438\u9644\u7279\u6027\u9650\u5236\u4e86\u90e8\u5206\u5c0f\u5206\u5b50\u836f\u7269\u7814\u7a76\uff0c\u800c\u73bb\u7483\u3001\u7845\u57fa\u82af\u7247\u7684\u52a0\u5de5\u6210\u672c\u8f83\u9ad8\uff1b\u6a21\u578b\u590d\u6742\u5ea6\u65b9\u9762\uff0c\u73b0\u6709\u82af\u7247\u591a\u6a21\u62df\u5355\u4e00 TME \u7279\u5f81\uff0c\u96be\u4ee5\u590d\u523b\u514d\u75ab\u7cfb\u7edf\u4e0e\u80bf\u7624\u7684\u5168\u8eab\u6027\u76f8\u4e92\u4f5c\u7528\uff1b\u4e34\u5e8a\u8f6c\u5316\u65b9\u9762\uff0c\u82af\u7247\u4e0e\u4e34\u5e8a\u6570\u636e\u7684\u5173\u8054\u6027\u9700\u8fdb\u4e00\u6b65\u9a8c\u8bc1\uff0c\u6807\u51c6\u5316\u6d41\u7a0b\uff08\u5982\u82af\u7247\u5236\u5907\u3001\u5b9e\u9a8c\u64cd\u4f5c\uff09\u5c1a\u672a\u5efa\u7acb\u3002\u6b64\u5916\uff0c\u5fae\u6d41\u63a7\u82af\u7247\u7684\u89c4\u6a21\u5316\u751f\u4ea7\uff08\u5982\u6279\u91cf\u5149\u523b\u3001\u81ea\u52a8\u5316\u952e\u5408\uff09\u4e0e\u9ad8\u901a\u91cf\u96c6\u6210\uff0c\u4ecd\u662f\u5de5\u4e1a\u754c\u5e94\u7528\u7684\u5173\u952e\u969c\u788d\u3002<\/p>\n\n\n\n

    2)    \u672a\u6765\u53d1\u5c55\u65b9\u5411<\/h3>\n\n\n\n
      \n
    1. \u6a21\u578b\u7cbe\u51c6\u5316\u4e0e\u590d\u6742\u5316\uff1a\u5f00\u53d1\u591a\u7ec6\u80de\u7c7b\u578b\u3001\u591a\u5668\u5b98\u96c6\u6210\u7684 \u201c\u4eba\u4f53\u82af\u7247\u201d\uff0c\u6574\u5408\u514d\u75ab\u7ec6\u80de\u3001\u57fa\u8d28\u7ec6\u80de\u3001\u8840\u7ba1\u7f51\u7edc\u4e0e\u795e\u7ecf\u5185\u5206\u6ccc\u7cfb\u7edf\uff0c\u6a21\u62df\u5b9e\u4f53\u7624\u7684\u7cfb\u7edf\u6027\u514d\u75ab\u5e94\u7b54\u3002\u7c7b\u5668\u5b98\u5fae\u6d41\u63a7\u82af\u7247\u5c06\u6210\u4e3a\u4e2a\u6027\u5316\u533b\u7597\u7684\u6838\u5fc3\u5de5\u5177\uff0c\u901a\u8fc7\u60a3\u8005\u6765\u6e90\u7c7b\u5668\u5b98\u4e0e\u514d\u75ab\u7ec6\u80de\u5171\u57f9\u517b\uff0c\u5b9e\u73b0\u6cbb\u7597\u65b9\u6848\u7684\u7cbe\u51c6\u9884\u6d4b\u3002<\/li>\n\n\n\n
    2. \u6280\u672f\u96c6\u6210\u4e0e\u81ea\u52a8\u5316\uff1a\u7ed3\u5408 AI \u4e0e\u673a\u5668\u5b66\u4e60\u7684\u5fae\u6d41\u63a7\u82af\u7247\uff0c\u53ef\u5b9e\u73b0\u7ec6\u80de\u884c\u4e3a\u7684\u81ea\u52a8\u5206\u6790\u4e0e\u6570\u636e\u89e3\u8bfb\uff1b\u81ea\u52a8\u5316 perfusion \u7cfb\u7edf\u3001\u673a\u5668\u4eba\u6db2\u4f53\u5904\u7406\u4e0e\u82af\u7247\u7684\u96c6\u6210\uff0c\u5c06\u63d0\u5347\u5b9e\u9a8c\u901a\u91cf\u4e0e\u91cd\u590d\u6027\uff0c\u63a8\u52a8\u836f\u7269\u7b5b\u9009\u5e94\u7528\u3002<\/li>\n\n\n\n
    3. \u6750\u6599\u521b\u65b0\u4e0e\u5de5\u827a\u4f18\u5316\uff1a\u65b0\u578b\u751f\u7269\u76f8\u5bb9\u6027\u6750\u6599\uff08\u5982\u975e\u52a8\u7269\u6e90 hydrogel\u3001\u53ef\u964d\u89e3\u805a\u5408\u7269\uff09\u7684\u5f00\u53d1\uff0c\u5c06\u964d\u4f4e\u82af\u7247\u7684\u751f\u7269\u5b89\u5168\u6027\u98ce\u9669\uff1bMEMS \u52a0\u5de5\u5de5\u827a\u7684\u4f18\u5316\uff08\u5982\u6fc0\u5149\u7eb3\u7c73\u52a0\u5de5\u30013D \u6253\u5370\u6a21\u5177\uff09\u5c06\u964d\u4f4e\u82af\u7247\u5b9a\u5236\u6210\u672c\uff0c\u5b9e\u73b0\u89c4\u6a21\u5316\u751f\u4ea7\u3002<\/li>\n\n\n\n
    4. \u4e34\u5e8a\u8f6c\u5316\u4e0e\u76d1\u7ba1\u8ba4\u53ef\uff1a\u5efa\u7acb\u5fae\u6d41\u63a7\u82af\u7247\u4e0e\u4e34\u5e8a\u7ec8\u70b9\u7684\u76f8\u5173\u6027\u6570\u636e\u5e93\uff0c\u63a8\u52a8\u76d1\u7ba1\u673a\u6784\u5bf9\u82af\u7247\u9884\u4e34\u5e8a\u6570\u636e\u7684\u8ba4\u53ef\uff1b\u5f00\u53d1\u4fbf\u643a\u5f0f\u5fae\u6d41\u63a7\u68c0\u6d4b\u8bbe\u5907\uff0c\u5b9e\u73b0\u514d\u75ab\u6cbb\u7597\u7597\u6548\u7684\u5b9e\u65f6\u76d1\u6d4b\uff08\u5982\u5faa\u73af\u80bf\u7624\u7ec6\u80de PD-L1 \u8868\u8fbe\u68c0\u6d4b\uff09\u3002<\/li>\n<\/ol>\n\n\n\n

      \u5fae\u6d41\u63a7\u6280\u672f\u51ed\u501f\u5176\u8ff7\u4f60\u5316\u3001\u7cbe\u51c6\u5316\u3001\u9ad8\u901a\u91cf\u7684\u4f18\u52bf\uff0c\u5df2\u6210\u4e3a\u5b9e\u4f53\u7624\u514d\u75ab\u6cbb\u7597\u7814\u7a76\u7684\u9769\u547d\u6027\u5de5\u5177\u3002\u4ece PDMS \u82af\u7247\u7684\u57fa\u7840\u7814\u7a76\u5230\u5668\u5b98\u82af\u7247\u7684\u4e34\u5e8a\u8f6c\u5316\uff0c\u4ece\u7ec6\u80de\u76f8\u4e92\u4f5c\u7528\u673a\u5236\u5230\u8054\u5408\u7597\u6cd5\u7b5b\u9009\uff0c\u5fae\u6d41\u63a7\u6280\u672f\u6b63\u5168\u65b9\u4f4d\u7a81\u7834\u4f20\u7edf\u6a21\u578b\u7684\u5c40\u9650\u3002\u968f\u7740 MEMS \u52a0\u5de5\u3001\u8868\u9762\u4fee\u9970\u3001\u82af\u7247\u5b9a\u5236\u7b49\u6838\u5fc3\u6280\u672f\u7684\u4e0d\u65ad\u4f18\u5316\uff0c\u4ee5\u53ca\u591a\u5b66\u79d1\u4ea4\u53c9\uff08\u5982\u514d\u75ab\u751f\u7269\u5b66\u3001\u6750\u6599\u79d1\u5b66\u3001\u81ea\u52a8\u5316\u6280\u672f\uff09\u7684\u6df1\u5165\uff0c\u5fae\u6d41\u63a7\u82af\u7247\u5c06\u5728\u4e2a\u6027\u5316\u514d\u75ab\u6cbb\u7597\u3001\u836f\u7269\u7814\u53d1\u4e0e\u4e34\u5e8a\u51b3\u7b56\u4e2d\u53d1\u6325\u6838\u5fc3\u4f5c\u7528\uff0c\u4e3a\u5b9e\u4f53\u7624\u60a3\u8005\u5e26\u6765\u65b0\u7684\u6cbb\u7597\u5e0c\u671b\u3002\u672a\u6765\uff0c\u901a\u8fc7\u5b66\u672f\u754c\u4e0e\u5de5\u4e1a\u754c\u7684\u534f\u540c\u521b\u65b0\uff0c\u5fae\u6d41\u63a7\u6280\u672f\u5c06\u5b9e\u73b0\u4ece\u5b9e\u9a8c\u5ba4\u5230\u4e34\u5e8a\u7684\u8de8\u8d8a\uff0c\u6210\u4e3a\u514d\u75ab\u6cbb\u7597\u9886\u57df\u7684\u6838\u5fc3\u652f\u6491\u5e73\u53f0\u3002<\/p>\n\n\n\n

      \u53c2\u8003\u6587\u732e\uff1aDOI: 10.1039\/d0lc01305f<\/p>\n\n\n\n

      Dxfluidics Customized Products<\/h3>\n\n\n
      \n
      \"\"<\/figure>\n<\/div>\n\n\n

      Ordering Methods<\/h3>\n\n\n\n
      \n
      \"\"
      Taobao store<\/strong><\/figcaption><\/figure>\n\n\n\n
      \"\"
      \u7535\u8bdd\uff1a18112558497<\/figcaption><\/figure>\n\n\n\n
      \"\"
      E-mail\uff1asale@dxfluidics.com<\/strong><\/figcaption><\/figure>\n<\/figure>\n\n\n\n

      <\/p>","protected":false},"excerpt":{"rendered":"

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