{"id":4668,"date":"2025-08-28T10:02:34","date_gmt":"2025-08-28T02:02:34","guid":{"rendered":"https:\/\/www.dxfluidics.com\/?p=4668"},"modified":"2025-08-28T10:02:35","modified_gmt":"2025-08-28T02:02:35","slug":"%e5%be%ae%e6%b5%81%e4%bd%93%e8%8a%af%e7%89%87%e5%9c%a8%e8%a1%80%e8%84%91%e5%b1%8f%e9%9a%9c%e5%8a%9f%e8%83%bd%e8%b0%83%e6%8e%a7%e4%b8%8e%e5%b8%95%e9%87%91%e6%a3%ae%e7%97%85%e7%a0%94%e7%a9%b6%e4%b8%ad","status":"publish","type":"post","link":"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/4668\/%e5%be%ae%e6%b5%81%e4%bd%93%e8%8a%af%e7%89%87%e5%9c%a8%e8%a1%80%e8%84%91%e5%b1%8f%e9%9a%9c%e5%8a%9f%e8%83%bd%e8%b0%83%e6%8e%a7%e4%b8%8e%e5%b8%95%e9%87%91%e6%a3%ae%e7%97%85%e7%a0%94%e7%a9%b6%e4%b8%ad\/","title":{"rendered":"\u5fae\u6d41\u4f53\u82af\u7247\u5728\u8840\u8111\u5c4f\u969c\u529f\u80fd\u8c03\u63a7\u4e0e\u5e15\u91d1\u68ee\u75c5\u7814\u7a76\u4e2d\u7684\u5e94\u7528"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u53c2\u8003\u6587\u732e\uff1aDOI&nbsp;10.3389\/fnagi.2025.1599509<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1.&nbsp;&nbsp;&nbsp; \u5fae\u6d41\u4f53\u82af\u7247\u6280\u672f\u539f\u7406\u4e0e\u65f6\u7a7a\u68af\u5ea6\u6a21\u62df<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.dxfluidics.com\/en\/microfluidic-chip\/custom-chip\/\">\u5fae\u6d41\u4f53\u82af\u7247\u6280\u672f<\/a>\u4ee5\u5fae\u7c73\u7ea7\u901a\u9053\u4e3a\u6838\u5fc3\uff0c\u901a\u8fc7\u7cbe\u51c6\u64cd\u63a7\u6d41\u4f53\u8fd0\u52a8\u6784\u5efa\u4eff\u751f\u5fae\u73af\u5883\uff0c\u5176\u6838\u5fc3\u4f18\u52bf\u5728\u4e8e\u5bf9\u4f53\u5185 \u201c\u65f6\u7a7a\u68af\u5ea6\u201d \u7684\u52a8\u6001\u6a21\u62df\u3002 \u8fd9\u7c7b\u82af\u7247\u591a\u91c7\u7528 <a href=\"https:\/\/www.dxfluidics.com\/en\/product\/microfluidic-chip\/custom-chip\/146\/pdms\u82af\u7247\/\">PDMS (polydimethylsiloxane)<\/a>\u3001\u73bb\u7483\u7b49\u900f\u660e\u4e14\u751f\u7269\u76f8\u5bb9\u6027\u4f18\u5f02\u7684\u6750\u6599\uff0c\u7ecf <a href=\"https:\/\/www.dxfluidics.com\/en\/microfluidic-device\/mems\u8bbe\u5907\/\">MEMS \u52a0\u5de5\u6280\u672f<\/a>\uff08\u5982<a href=\"https:\/\/www.dxfluidics.com\/en\/product\/microfluidic-device\/desktop-lithography-machine-exposure-machine\/dingxu-scientific-research-exposure-machine\/1270\/\u684c\u9762\u5149\u523b\u673a-\u66dd\u5149\u673a\/\">lithography<\/a>\u3001\u6df1\u7845\u523b\u8680\uff09\u5236\u5907\u800c\u6210\uff0c\u53ef\u96c6\u6210\u5fae\u6d41\u9053\u3001\u68af\u5ea6\u751f\u6210\u533a\u3001\u7ec6\u80de\u57f9\u517b\u5ba4\u7b49\u529f\u80fd\u5355\u5143\uff0c\u5b9e\u73b0\u5bf9\u5316\u5b66\u6d53\u5ea6\u3001\u6d41\u4f53\u526a\u5207\u529b\u7b49\u591a\u53c2\u6570\u7684\u7cbe\u786e\u8c03\u63a7\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201c\u65f6\u7a7a\u68af\u5ea6\u201d \u6307\u5fae\u73af\u5883\u4e2d\u5316\u5b66\u56e0\u5b50\uff08\u5982\u708e\u75c7\u4ecb\u8d28\u3001\u6c27\u6d53\u5ea6\uff09\u7684\u7a7a\u95f4\u5206\u5e03\u5dee\u5f02\u4e0e\u65f6\u95f4\u52a8\u6001\u53d8\u5316\u7684\u534f\u540c\u4f5c\u7528\u3002 \u5728\u751f\u7406\u72b6\u6001\u4e0b\uff0c\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u53d7\u8840\u6d41\u526a\u5207\u529b\u68af\u5ea6\u8c03\u63a7\uff0c\u7ef4\u6301\u8840\u8111\u5c4f\u969c\uff08BBB\uff09\u7684\u7d27\u5bc6\u8fde\u63a5\uff1b \u800c\u5728\u75c5\u7406\u8fc7\u7a0b\u4e2d\uff0c\u708e\u75c7\u56e0\u5b50\u7684\u6d53\u5ea6\u68af\u5ea6\u4f1a\u9a71\u52a8\u795e\u7ecf\u708e\u75c7\u7ea7\u8054\u53cd\u5e94\u3002 \u4f20\u7edf Transwell \u6a21\u578b\u56e0\u9759\u6001\u57f9\u517b\u65e0\u6cd5\u590d\u73b0\u8fd9\u4e9b\u52a8\u6001\u4fe1\u53f7\uff0c\u800c\u5fae\u6d41\u4f53\u82af\u7247\u901a\u8fc7\u5206\u53c9\u901a\u9053\u8bbe\u8ba1\u3001\u6d41\u4f53\u529b\u5b66\u8c03\u63a7\uff0c\u53ef\u751f\u6210\u7a33\u5b9a\u7684\u5316\u5b66\u68af\u5ea6\uff08\u5982 TNF-\u03b1\u3001IL-6 \u6d53\u5ea6\u68af\u5ea6\uff09\u548c\u7269\u7406\u68af\u5ea6\uff08\u5982 0-10 dyn\/cm\u00b2 \u7684\u526a\u5207\u529b\u68af\u5ea6\uff09\uff0c\u4e3a\u7814\u7a76\u7ec6\u80de\u5bf9\u52a8\u6001\u5fae\u73af\u5883\u7684\u54cd\u5e94\u63d0\u4f9b\u4e86\u7406\u60f3\u5e73\u53f0\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2.&nbsp;&nbsp;&nbsp; \u8840\u8111\u5c4f\u969c\u529f\u80fd\u7684\u52a8\u6001\u8c03\u63a7\u673a\u5236<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"554\" height=\"258\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72471-4.png\" alt=\"\" class=\"wp-image-4670\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72471-4.png 554w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72471-4-18x8.png 18w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\" style=\"font-style:italic;font-weight:300\">\u8840\u8111\u5c4f\u969c\u7684\u7ec4\u6210\u53ca\u5173\u952e\u7279\u5f81&nbsp;\uff08A\uff09&nbsp;\u6a2a\u622a\u9762\u56fe\u5c55\u793a\u4e86\u795e\u7ecf\u8840\u7ba1\u5355\u5143\uff0c\u5176\u7531\u5185\u76ae\u7ec6\u80de\u3001\u5468\u7ec6\u80de\u3001\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u3001\u57fa\u5e95\u819c\u3001\u795e\u7ecf\u5143\u548c\u514d\u75ab\u7ec6\u80de\u7ec4\u6210\u3002\uff08B\uff09&nbsp;\u4e00\u4e2a\u6709\u6548\u7684\u4f53\u5916\u8840\u8111\u5c4f\u969c\u6a21\u578b\u5e94\u6210\u529f\u5177\u5907\u4ee5\u4e0b\u57fa\u672c\u7279\u5f81\uff1a\uff081\uff09&nbsp;\u8868\u8fbe\u529f\u80fd\u6027\u7d27\u5bc6\u8fde\u63a5\u7684\u5185\u76ae\u7ec6\u80de\uff1b\uff082\uff09&nbsp;\u4e0e\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u5171\u57f9\u517b\u4ee5\u6a21\u62df\u751f\u7406\u6761\u4ef6\uff1b\uff083\uff09&nbsp;\u66b4\u9732\u4e8e\u526a\u5207\u5e94\u529b\u4ee5\u6a21\u62df\u8840\u7ba1\u52a8\u529b\u5b66\uff1b\uff084\uff09&nbsp;\u5bf9\u5316\u5408\u7269\u5177\u6709\u9009\u62e9\u6027\u901a\u900f\u6027\uff1b\uff085\uff09&nbsp;\u7d27\u5bc6\u8fde\u63a5\u5904\u5177\u6709\u9ad8\u8de8\u5185\u76ae\u7535\u963b\uff08TEER\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u8111\u5c4f\u969c\u4f5c\u4e3a\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u7684\u4fdd\u62a4\u6027\u5c4f\u969c\uff0c\u7531\u5185\u76ae\u7ec6\u80de\u3001\u5468\u7ec6\u80de\u3001\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u7b49\u6784\u6210\uff0c\u5176\u5b8c\u6574\u6027\u4f9d\u8d56\u4e8e\u7d27\u5bc6\u8fde\u63a5\u86cb\u767d\uff08\u5982&nbsp;claudin-5\u3001occludin\uff09\u7684\u8868\u8fbe\u4e0e\u7ec6\u80de\u95f4\u4fe1\u53f7\u4f20\u5bfc\u3002\u5fae\u6d41\u4f53\u82af\u7247\u901a\u8fc7\u6784\u5efa\u591a\u7ec6\u80de\u5171\u57f9\u517b\u7cfb\u7edf\uff0c\u63ed\u793a\u4e86\u5fae\u73af\u5883\u68af\u5ea6\u5bf9\u8840\u8111\u5c4f\u969c\u529f\u80fd\u7684\u590d\u6742\u8c03\u63a7\u673a\u5236\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u5316\u5b66\u68af\u5ea6\u65b9\u9762\uff0c\u4f4e\u6c27\u73af\u5883\u53ef\u6fc0\u6d3b\u5185\u76ae\u7ec6\u80de\u7684&nbsp;HIF-1\u03b1&nbsp;\u901a\u8def\uff0c\u4e0a\u8c03&nbsp;VEGF&nbsp;\u8868\u8fbe\uff0c\u5bfc\u81f4\u7d27\u5bc6\u8fde\u63a5\u86cb\u767d\u964d\u89e3\uff1b\u800c\u708e\u75c7\u56e0\u5b50\u68af\u5ea6\uff08\u5982&nbsp;TNF-\u03b1\uff09\u5219\u901a\u8fc7\u6fc0\u6d3b&nbsp;NF-\u03baB&nbsp;\u4fe1\u53f7\u901a\u8def\uff0c\u589e\u52a0\u8840\u8111\u5c4f\u969c\u901a\u900f\u6027\u3002\u7269\u7406\u68af\u5ea6\u4e2d\uff0c\u6d41\u4f53\u526a\u5207\u529b\u901a\u8fc7&nbsp;PI3K\/Akt&nbsp;\u901a\u8def\u8c03\u63a7\u5185\u76ae\u7ec6\u80de\u6781\u6027\uff0c\u9ad8\u526a\u5207\u529b\u53ef\u4fc3\u8fdb&nbsp;ZO-1&nbsp;\u86cb\u767d\u805a\u96c6\uff0c\u589e\u5f3a\u5c4f\u969c\u529f\u80fd\u3002\u4f8b\u5982\uff0c\u5728\u6a21\u62df\u8840\u7ba1\u8109\u52a8\u7684\u5fae\u6d41\u63a7\u6a21\u578b\u4e2d\uff0c\u5185\u76ae\u7ec6\u80de\u6cbf\u8840\u6d41\u65b9\u5411\u6392\u5217\uff0cPECAM-1&nbsp;\u8868\u8fbe\u4e0a\u8c03\uff0c\u663e\u8457\u63d0\u5347\u8840\u8111\u5c4f\u969c\u7684\u5b8c\u6574\u6027\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3.&nbsp;&nbsp;&nbsp; \u5e15\u91d1\u68ee\u75c5\u75c5\u7406\u6f14\u5316\u7684\u5fae\u73af\u5883\u673a\u5236<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e15\u91d1\u68ee\u75c5\uff08PD\uff09\u7684\u75c5\u7406\u8fdb\u7a0b\u4e0e\u8840\u8111\u5c4f\u969c\u529f\u80fd\u5f02\u5e38\u5bc6\u5207\u76f8\u5173\u3002\u4e34\u5e8a\u7814\u7a76\u8868\u660e\uff0cPD&nbsp;\u60a3\u8005\u8111\u5fae\u8840\u7ba1\u4e2d&nbsp;claudin-5&nbsp;\u548c&nbsp;occludin&nbsp;\u8868\u8fbe\u4e0b\u8c03\uff0cP&nbsp;&#8211;&nbsp;\u7cd6\u86cb\u767d\u529f\u80fd\u53d7\u635f\uff0c\u5bfc\u81f4\u8840\u8111\u5c4f\u969c\u901a\u900f\u6027\u589e\u52a0\uff0c\u5916\u5468\u708e\u75c7\u56e0\u5b50\uff08\u5982&nbsp;IL-6\uff09\u548c\u795e\u7ecf\u6bd2\u7d20\uff08\u5982&nbsp;6&nbsp;&#8211;&nbsp;\u7f9f\u57fa\u591a\u5df4\u80fa\uff09\u6e17\u5165\u8111\u5b9e\u8d28\uff0c\u5f62\u6210\u5c40\u90e8\u6d53\u5ea6\u68af\u5ea6\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5fae\u6d41\u4f53\u82af\u7247\u901a\u8fc7\u6784\u5efa&nbsp;\u201c\u9ed1\u8d28\u82af\u7247\u201d&nbsp;\u6a21\u578b\uff0c\u6a21\u62df\u4e86&nbsp;PD&nbsp;\u75c5\u7406\u5fae\u73af\u5883\u7684\u5173\u952e\u7279\u5f81\uff1a\u5c06\u4eba\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u5206\u5316\u7684\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u4e0e\u8840\u8111\u5c4f\u969c\u5185\u76ae\u7ec6\u80de\u5171\u57f9\u517b\uff0c\u5f15\u5165&nbsp;\u03b1-&nbsp;\u7a81\u89e6\u6838\u86cb\u767d\uff08\u03b1-syn\uff09\u9884\u5236\u7ea4\u7ef4\u540e\uff0c\u53ef\u89c2\u5bdf\u5230&nbsp;pSer129-\u03b1Syn&nbsp;\u805a\u96c6\u3001\u7ebf\u7c92\u4f53\u529f\u80fd\u5f02\u5e38\u53ca\u795e\u7ecf\u708e\u75c7\u53cd\u5e94\uff0c\u540c\u65f6\u4f34\u968f&nbsp;TEER\uff08\u8de8\u5185\u76ae\u7535\u963b\uff09\u503c\u4e0b\u964d\uff0c\u76f4\u89c2\u518d\u73b0\u8840\u8111\u5c4f\u969c\u7834\u574f\u4e0e\u795e\u7ecf\u5143\u9000\u53d8\u7684\u76f8\u4e92\u4f5c\u7528\u3002\u6b64\u5916\uff0c\u82af\u7247\u6a21\u578b\u8fd8\u63ed\u793a\u4e86\u4ee3\u8c22\u68af\u5ea6\u7684\u4f5c\u7528&nbsp;\u2014\u2014&nbsp;\u7ebf\u7c92\u4f53\u529f\u80fd\u969c\u788d\u5bfc\u81f4\u7684\u80fd\u91cf\u5206\u5e03\u5931\u8861\uff0c\u4f1a\u52a0\u5267\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u7684\u6c27\u5316\u635f\u4f24\uff0c\u5f62\u6210\u75c5\u7406\u5faa\u73af\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4.&nbsp;&nbsp;&nbsp; \u5fae\u6d41\u4f53\u82af\u7247\u7684\u5b9e\u9a8c\u8bbe\u8ba1\u4e0e\u6a21\u578b\u6784\u5efa<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u6784\u5efa\u00a0PD\u00a0\u75c5\u7406\u6a21\u62df\u6a21\u578b\u9700\u6574\u5408\u591a\u53c2\u6570\u8c03\u63a7\u7b56\u7565\u3002\u82af\u7247\u8bbe\u8ba1\u5e38\u91c7\u7528\u591a\u5c42\u7ed3\u6784\uff08\u5982\u00a0<a href=\"https:\/\/www.dxfluidics.com\/en\/product\/microfluidic-device\/laser-equipment\/laser-bonding-machine\/4381\/\u6fc0\u5149\u952e\u5408\u673a\/\">PDMS\u00a0\u57fa\u7247\u4e0e\u73bb\u7483\u5c42\u7ed3\u5408<\/a>\uff09\uff0c\u901a\u8fc7\u4ea4\u53c9\u901a\u9053\u5f15\u5165\u52a8\u6001\u6d41\u4f53\uff0c\u5229\u7528\u591a\u5b54\u819c\u5206\u9694\u4e0d\u540c\u7ec6\u80de\u7c7b\u578b\uff08\u5982\u5185\u76ae\u7ec6\u80de\u4e0e\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\uff09\uff0c\u5e76\u96c6\u6210\u00a0TEER\u00a0\u4f20\u611f\u5668\u5b9e\u65f6\u76d1\u6d4b\u5c4f\u969c\u5b8c\u6574\u6027\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"554\" height=\"419\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72472-5.png\" alt=\"\" class=\"wp-image-4671\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72472-5.png 554w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72472-5-16x12.png 16w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\" style=\"font-style:italic;font-weight:300\">\u8840\u8111\u5c4f\u969c\u5fae\u6d41\u63a7\u82af\u7247\uff1a\u5728\u6b64\uff0c\u6211\u4eec\u5c55\u793a\u4e86\u4e00\u79cd\u5148\u8fdb\u7684\u591a\u5c42\u5fae\u6d41\u63a7\u88c5\u7f6e\uff0c\u5176\u8bbe\u8ba1\u7075\u611f\u6765\u6e90\u4e8e\u7f57\u65af\u00b7\u5e03\u65af\u7b49\u4eba\uff0c\u8be5\u88c5\u7f6e\u7531\u56db\u4e2a\u805a\u4e8c\u7532\u57fa\u7845\u6c27\u70f7\uff08PDMS\uff09\u57fa\u677f\u3001\u4e24\u4e2a\u73bb\u7483\u5c42\u4ee5\u53ca\u4f4d\u4e8ePDMS\u7ed3\u6784\u4e2d\u5fc3\u4f4d\u7f6e\u7684\u591a\u5b54\u805a\u78b3\u9178\u916f\u8584\u819c\u7ec4\u6210\u3002\u8be5\u96c6\u6210\u88c5\u7f6e\u5177\u6709\u4e24\u6761\u5782\u76f4\u76f8\u4ea4\u7684\u901a\u9053\uff0c\u7528\u4e8e\u52a8\u6001\u5f15\u5165\u6d41\u4f53\uff1b\u5728\u901a\u9053\u4ea4\u53c9\u5904\u8bbe\u6709\u591a\u5b54\u819c\uff0c\u4ee5\u4fc3\u8fdb\u7ec6\u80de\u57f9\u517b\uff1b\u8fd8\u5d4c\u5165\u4e86\u7535\u6781\uff0c\u7528\u4e8e\u76d1\u6d4b\u8de8\u4e0a\u76ae\u7535\u963b\uff08TEER\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u529f\u80fd\u9a8c\u8bc1\u65b9\u9762\uff0c\u8367\u5149&nbsp;tracer&nbsp;\u5206\u6790\u53ef\u91cf\u5316\u7269\u8d28\u8de8\u5c4f\u969c\u8fd0\u8f93\u6548\u7387\uff0c\u800c&nbsp;Western&nbsp;blot&nbsp;\u548c\u514d\u75ab\u8367\u5149\u5219\u7528\u4e8e\u68c0\u6d4b\u7d27\u5bc6\u8fde\u63a5\u86cb\u767d\uff08\u5982&nbsp;ZO-1\uff09\u548c\u708e\u75c7\u56e0\u5b50\u7684\u8868\u8fbe\u53d8\u5316\u3002\u7ed3\u5408\u8ba1\u7b97\u6d41\u4f53\u52a8\u529b\u5b66\uff08CFD\uff09\u6a21\u62df\uff0c\u53ef\u9884\u6d4b\u82af\u7247\u5185\u68af\u5ea6\u5206\u5e03\u4e0e\u526a\u5207\u529b\u573a\uff0c\u4f18\u5316\u5b9e\u9a8c\u53c2\u6570\u3002\u4f8b\u5982\uff0c\u901a\u8fc7\u8c03\u63a7&nbsp;6&nbsp;&#8211;&nbsp;\u7f9f\u57fa\u591a\u5df4\u80fa\u7684\u6d53\u5ea6\u68af\u5ea6\uff0c\u7814\u7a76\u8005\u5728\u82af\u7247\u4e2d\u6210\u529f\u8bf1\u5bfc&nbsp;PC12&nbsp;\u7ec6\u80de\u7684\u51cb\u4ea1\u68af\u5ea6\uff0c\u4e3a&nbsp;PD&nbsp;\u795e\u7ecf\u6bd2\u6027\u673a\u5236\u7814\u7a76\u63d0\u4f9b\u4e86\u91cf\u5316\u6a21\u578b\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5.&nbsp;&nbsp;&nbsp; \u6280\u672f\u6311\u6218\u4e0e\u672a\u6765\u5c55\u671b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f53\u524d\u5fae\u6d41\u4f53\u82af\u7247\u6280\u672f\u9762\u4e34\u6807\u51c6\u5316\u4e0e\u751f\u7406\u76f8\u5173\u6027\u4e24\u5927\u6311\u6218\u3002\u82af\u7247\u5236\u5907\u4f9d\u8d56<a href=\"https:\/\/www.dxfluidics.com\/en\/product\/consumables\/906\/su-8\u5149\u523b\u80f6-\u663e\u5f71\u6db2\/\">Photoresist<\/a>\u6a21\u5177\u4e0e\u00a0PDMS\u00a0\u6d47\u7b51\u5de5\u827a\uff0c\u4f46\u4e0d\u540c\u5b9e\u9a8c\u5ba4\u7684\u6750\u6599\u9009\u62e9\uff08\u5982\u00a0PDMS\u00a0\u4e0e\u00a0COP\uff09\u548c\u52a0\u5de5\u6d41\u7a0b\u5dee\u5f02\uff0c\u5bfc\u81f4\u6a21\u578b\u91cd\u590d\u6027\u4e0d\u8db3\uff1b\u957f\u671f\u57f9\u517b\u4e2d\u7ec6\u80de\u8868\u578b\u4e0d\u7a33\u5b9a\u3001\u591a\u5668\u5b98\u534f\u540c\u8c03\u63a7\u7f3a\u5931\u7b49\u95ee\u9898\uff0c\u4e5f\u9650\u5236\u4e86\u5176\u4e34\u5e8a\u8f6c\u5316\u4ef7\u503c\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672a\u6765\u53d1\u5c55\u9700\u805a\u7126\u591a\u6280\u672f\u878d\u5408\uff1a\u5229\u7528\u00a0<a href=\"https:\/\/www.dxfluidics.com\/en\/microfluidic-device\/3d\u6253\u5370\u8bbe\u5907\/\">3D\u00a0\u6253\u5370<\/a>\u6784\u5efa\u590d\u6742\u7c7b\u5668\u5b98\u82af\u7247\uff0c\u7ed3\u5408\u00a0CRISPR\u00a0\u57fa\u56e0\u7f16\u8f91\u4f18\u5316\u7ec6\u80de\u6a21\u578b\uff1b\u901a\u8fc7\u00a0AI\u00a0\u7b97\u6cd5\u6574\u5408\u591a\u7ec4\u5b66\u6570\u636e\uff08\u8f6c\u5f55\u7ec4\u3001\u86cb\u767d\u7ec4\uff09\uff0c\u5b9e\u73b0\u68af\u5ea6\u4fe1\u53f7\u4e0e\u5206\u5b50\u673a\u5236\u7684\u5173\u8054\u5206\u6790\u3002\u8de8\u5b66\u79d1\u534f\u4f5c\u5c06\u63a8\u52a8\u82af\u7247\u6807\u51c6\u5316\u6846\u67b6\u7684\u5efa\u7acb\uff0c\u4f8b\u5982\u5236\u5b9a\u7edf\u4e00\u7684\u00a0BBB\u00a0\u82af\u7247\u6027\u80fd\u8bc4\u4ef7\u6307\u6807\uff08\u5982\u00a0TEER\u00a0\u9608\u503c\u3001\u00a0permeability\u00a0\u6807\u51c6\uff09\u3002\u6b64\u5916\uff0c\u8de8\u5668\u5b98\u82af\u7247\uff08\u5982\u8111\u00a0&#8211;\u00a0\u80a0\u8f74\u82af\u7247\uff09\u7684\u5f00\u53d1\uff0c\u6709\u671b\u63ed\u793a\u00a0PD\u00a0\u7cfb\u7edf\u6027\u75c5\u7406\u673a\u5236\uff0c\u4e3a\u4e2a\u6027\u5316\u836f\u7269\u7b5b\u9009\u4e0e\u9776\u5411\u6cbb\u7597\u63d0\u4f9b\u5168\u65b0\u5e73\u53f0\u3002 \u5fae\u6d41\u4f53\u82af\u7247\u6280\u672f\u901a\u8fc7\u590d\u73b0\u751f\u7269\u5fae\u73af\u5883\u7684\u52a8\u6001\u7279\u5f81\uff0c\u4e0d\u4ec5\u6df1\u5316\u4e86\u5bf9\u8840\u8111\u5c4f\u969c\u4e0e\u5e15\u91d1\u68ee\u75c5\u76f8\u4e92\u4f5c\u7528\u7684\u7406\u89e3\uff0c\u66f4\u63a8\u52a8\u4e86\u4ece\u57fa\u7840\u7814\u7a76\u5230\u4e34\u5e8a\u5e94\u7528\u7684\u8de8\u8d8a\u3002\u968f\u7740\u6280\u672f\u7684\u4e0d\u65ad\u8fed\u4ee3\uff0c\u5176\u5728\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u673a\u5236\u7814\u7a76\u4e0e\u7cbe\u51c6\u533b\u5b66\u9886\u57df\u7684\u5e94\u7528\u524d\u666f\u5c06\u6108\u53d1\u5e7f\u9614\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading has-pale-cyan-blue-background-color has-background has-medium-font-size\">Dxfluidics Products<\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"851\" height=\"548\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/image-16.png\" alt=\"\" class=\"wp-image-1662\" style=\"width:747px;height:auto\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/image-16.png 851w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/image-16-600x386.png 600w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/image-16-768x495.png 768w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/image-16-18x12.png 18w\" sizes=\"auto, (max-width: 851px) 100vw, 851px\" \/><\/figure>\n<\/div>\n\n\n<figure class=\"wp-block-table has-small-font-size\"><table><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"2\">Product Code<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"2\">Outline<br>\uff08mm\uff09<\/td><td class=\"has-text-align-center\" data-align=\"center\" colspan=\"2\">microcolumn<br>\uff08um\uff09<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"2\">Offset angle <br>\uff08um\uff09<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"2\">Column space<br>\uff08um\uff09<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"2\">Sorting channel length <br>\uff08mm\uff09<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"2\">Channel height <br>\uff08um\uff09<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"2\">Material<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"2\">Price <br>(CNY)<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Shape<\/td><td class=\"has-text-align-center\" data-align=\"center\">Side length\/Diameter<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">800001<\/td><td class=\"has-text-align-center\" data-align=\"center\">75*25<\/td><td class=\"has-text-align-center\" data-align=\"center\">triangle<\/td><td class=\"has-text-align-center\" data-align=\"center\">60<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">85<\/td><td class=\"has-text-align-center\" data-align=\"center\">35.5<\/td><td class=\"has-text-align-center\" data-align=\"center\">50<\/td><td class=\"has-text-align-center\" data-align=\"center\">PDMS+glass<\/td><td class=\"has-text-align-center\" data-align=\"center\">500<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">800002<\/td><td class=\"has-text-align-center\" data-align=\"center\">75*25<\/td><td class=\"has-text-align-center\" data-align=\"center\">triangle<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">40<\/td><td class=\"has-text-align-center\" data-align=\"center\">55<\/td><td class=\"has-text-align-center\" data-align=\"center\">50<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"3\">PDMS+glass<\/td><td class=\"has-text-align-center\" data-align=\"center\" rowspan=\"3\">600<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">800002-1<\/td><td class=\"has-text-align-center\" data-align=\"center\">75*25<\/td><td class=\"has-text-align-center\" data-align=\"center\">circle<\/td><td class=\"has-text-align-center\" data-align=\"center\">30<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">40<\/td><td class=\"has-text-align-center\" data-align=\"center\">55<\/td><td class=\"has-text-align-center\" data-align=\"center\">50<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">800002-2<\/td><td class=\"has-text-align-center\" data-align=\"center\">75*25<\/td><td class=\"has-text-align-center\" data-align=\"center\">triangle<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">40<\/td><td class=\"has-text-align-center\" data-align=\"center\">55<\/td><td class=\"has-text-align-center\" data-align=\"center\">50<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">800003<\/td><td class=\"has-text-align-center\" data-align=\"center\">75*25<\/td><td class=\"has-text-align-center\" data-align=\"center\">triangle<\/td><td class=\"has-text-align-center\" data-align=\"center\">30<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">65<\/td><td class=\"has-text-align-center\" data-align=\"center\">28<\/td><td class=\"has-text-align-center\" data-align=\"center\">50<\/td><td class=\"has-text-align-center\" data-align=\"center\">PDMS+glass<\/td><td class=\"has-text-align-center\" data-align=\"center\">500<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">800004<\/td><td class=\"has-text-align-center\" data-align=\"center\">75*25<\/td><td class=\"has-text-align-center\" data-align=\"center\">circle<\/td><td class=\"has-text-align-center\" data-align=\"center\">40<\/td><td class=\"has-text-align-center\" data-align=\"center\">9<\/td><td class=\"has-text-align-center\" data-align=\"center\">80<\/td><td class=\"has-text-align-center\" data-align=\"center\">4mm*3<\/td><td class=\"has-text-align-center\" data-align=\"center\">50<\/td><td class=\"has-text-align-center\" data-align=\"center\">PDMS+glass<\/td><td class=\"has-text-align-center\" data-align=\"center\">500<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">The prices listed are for mainland China and are in Chinese Yuan (CNY,\u00a5). For regions outside mainland China, please contact customer service for a quote.(sale@dxfluidics.com)<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading has-pale-cyan-blue-background-color has-background has-medium-font-size\">Ordering Methods<\/h3>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"140\" height=\"140\" data-id=\"1378\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2023\/10\/image-26.png\" alt=\"\" class=\"wp-image-1378\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2023\/10\/image-26.png 140w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2023\/10\/image-26-100x100.png 100w\" sizes=\"auto, (max-width: 140px) 100vw, 140px\" \/><figcaption class=\"wp-element-caption\">Taobao store<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"396\" height=\"396\" data-id=\"823\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2023\/02\/\u5434\u7115.png\" alt=\"\" class=\"wp-image-823\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2023\/02\/\u5434\u7115.png 396w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2023\/02\/\u5434\u7115-300x300.png 300w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2023\/02\/\u5434\u7115-100x100.png 100w\" sizes=\"auto, (max-width: 396px) 100vw, 396px\" \/><figcaption class=\"wp-element-caption\">           Wechat\uff08TEL:18112558497)<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"900\" height=\"720\" data-id=\"1599\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/R.jpg\" alt=\"\" class=\"wp-image-1599\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/R.jpg 900w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/R-600x480.jpg 600w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/R-768x614.jpg 768w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2024\/01\/R-15x12.jpg 15w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><figcaption class=\"wp-element-caption\">   E-mail\uff1asale@dxfluidics.com<\/figcaption><\/figure>\n<\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>\u53c2\u8003\u6587\u732e\uff1aDOI&nbsp;10.3389\/fnagi.2025.1599509 1.&nbsp;&nbsp; [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","footnotes":""},"categories":[5],"tags":[],"class_list":["post-4668","post","type-post","status-publish","format-standard","hentry","category-information"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin 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