{"id":4634,"date":"2025-08-21T10:01:30","date_gmt":"2025-08-21T02:01:30","guid":{"rendered":"https:\/\/www.dxfluidics.com\/?p=4634"},"modified":"2025-08-26T13:34:48","modified_gmt":"2025-08-26T05:34:48","slug":"%e5%be%ae%e6%b5%81%e6%8e%a7%e8%8a%af%e7%89%87%e9%aa%a8%e5%85%b3%e8%8a%82%e7%82%8e%e5%85%b3%e8%8a%82%e7%82%8e%e7%97%87%e6%a8%a1%e5%9e%8b%e5%ba%94%e7%94%a8","status":"publish","type":"post","link":"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/4634\/%e5%be%ae%e6%b5%81%e6%8e%a7%e8%8a%af%e7%89%87%e9%aa%a8%e5%85%b3%e8%8a%82%e7%82%8e%e5%85%b3%e8%8a%82%e7%82%8e%e7%97%87%e6%a8%a1%e5%9e%8b%e5%ba%94%e7%94%a8\/","title":{"rendered":"\u5fae\u6d41\u63a7\u82af\u7247\u5728\u9aa8\u5173\u8282\u708e\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u5e94\u7528 | \u6280\u672f\u539f\u7406\u4e0e\u5b9e\u9a8c\u9a8c\u8bc1"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u5728\u9aa8\u5173\u8282\u708e\uff08OA\uff09\u7814\u7a76\u4e2d\uff0c\u4f20\u7edf\u5355\u57f9\u517b\u6a21\u578b\u56e0\u7f3a\u4e4f\u7ec6\u80de\u95f4\u901a\u8baf\u3001\u52a8\u7269\u6a21\u578b\u56e0\u7269\u79cd\u5dee\u5f02\u96be\u4ee5\u7cbe\u51c6\u6a21\u62df\u4f53\u5185\u5173\u8282\u5fae\u73af\u5883\uff0c\u6210\u4e3a\u5236\u7ea6\u75c5\u7406\u673a\u5236\u7814\u7a76\u4e0e\u836f\u7269\u7814\u53d1\u7684\u5173\u952e\u74f6\u9888\u3002\u4e3a\u6b64\uff0c\u8fd1\u671f\u7814\u7a76\u56e2\u961f\u5f00\u53d1\u4e86<strong>\u5fae\u6d41\u63a7\u82af\u7247\u5728\u9aa8\u5173\u8282\u708e\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u5e94\u7528<\/strong>\u76f8\u5173\u6280\u672f\uff0c\u901a\u8fc7\u6574\u5408\u591a\u7c7b\u4eba\u4f53\u7ec6\u80de\u4e0e\u7cbe\u5bc6\u5fae\u73af\u5883\u8c03\u63a7\uff0c\u6784\u5efa\u51fa\u63a5\u8fd1\u751f\u7406\u72b6\u6001\u7684\u5065\u5eb7\u4e0e\u75be\u75c5\u4f53\u5916\u6a21\u578b\uff0c\u4e3a OA \u7814\u7a76\u7a81\u7834\u4f20\u7edf\u5c40\u9650\u63d0\u4f9b\u4e86\u5168\u65b0\u8def\u5f84\u3002\u672c\u6587\u5c06\u7cfb\u7edf\u89e3\u6790\u8be5\u5fae\u6d41\u63a7\u5171\u57f9\u517b\u7cfb\u7edf\u7684\u6784\u5efa\u539f\u7406\u3001\u6838\u5fc3\u4f18\u52bf\u3001\u6280\u672f\u652f\u6491\u53ca\u5e94\u7528\u524d\u666f\uff0c\u6df1\u5165\u9610\u8ff0\u5176\u5728\u9aa8\u5173\u8282\u708e\u57fa\u7840\u7814\u7a76\u4e0e\u4e34\u5e8a\u8f6c\u5316\u4e2d\u7684\u4ef7\u503c\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u53c2\u8003\u6587\u732e\uff1aDOI&nbsp;10.3389\/fphar.2025.1579228<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1.&nbsp;&nbsp;&nbsp; \u5fae\u6d41\u63a7\u82af\u7247\u5728\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u6784\u5efa\u4e0e\u521b\u65b0<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u6a21\u578b\u6784\u5efa\u4e2d\uff0c\u901a\u8fc7\u5411\u57f9\u517b\u57fa\u6dfb\u52a0&nbsp;IFN-\u03b3&nbsp;\u548c\u8102\u591a\u7cd6\uff08LPS\uff09\u8bf1\u5bfc\u5de8\u566c\u7ec6\u80de\u5411&nbsp;M1&nbsp;\u8868\u578b\u5206\u5316\uff0c\u7cbe\u51c6\u590d\u73b0\u4e86&nbsp;OA&nbsp;\u7684\u708e\u75c7\u5fae\u73af\u5883\u3002\u8fd9\u79cd\u8bbe\u8ba1\u4e0d\u4ec5\u7eb3\u5165\u4e86\u9aa8\u3001\u8f6f\u9aa8\u3001\u6ed1\u819c\u7ec4\u7ec7\u6765\u6e90\u7684\u7ec6\u80de\uff0c\u8fd8\u901a\u8fc7\u5fae\u6d41\u63a7\u7cfb\u7edf\u7684\u6d41\u52a8\u63a7\u5236\u5b9e\u73b0\u4e86\u7ec6\u80de\u95f4\u7684\u65c1\u5206\u6ccc\u4fe1\u53f7\u4f20\u9012\uff0c\u8f83\u4f20\u7edf\u9759\u6001\u57f9\u517b\u66f4\u63a5\u8fd1\u5728\u4f53\u5173\u8282\u7684\u591a\u7ec4\u7ec7\u4ea4\u4e92\u7279\u6027\u3002\u6b64\u5916\uff0c\u8be5\u7cfb\u7edf\u91c7\u7528\u60a3\u8005\u6765\u6e90\u7684\u539f\u4ee3\u7ec6\u80de\u800c\u975e\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSCs\uff09\uff0c\u907f\u514d\u4e86\u5e72\u7ec6\u80de\u5206\u5316\u4e0d\u5747\u5bfc\u81f4\u7684\u8868\u578b\u504f\u5dee\uff0c\u63d0\u5347\u4e86\u75be\u75c5\u6a21\u62df\u7684\u51c6\u786e\u6027\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"554\" height=\"309\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72471-3.png\" alt=\"\" class=\"wp-image-4635\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72471-3.png 554w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72471-3-18x10.png 18w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><figcaption class=\"wp-element-caption\">\u6ed1\u819c&nbsp;&#8211;&nbsp;\u8f6f\u9aa8\uff0c\u5176\u7ec4\u7ec7\u901a\u5e38\u76f8\u4e92\u4f5c\u7528\u5e76\u4f20\u9012\u4fe1\u53f7\uff0c\u4ee5\u7ef4\u6301\u529f\u80fd\u548c\u53cd\u5e94\u6027\u3002\u901a\u8fc7\u5171\u4eab\u7684\u7ec6\u80de\u57f9\u517b\u57fa\uff0c\u591a\u79cd\u7ec6\u80de\u7c7b\u578b\u76f8\u4e92\u6c9f\u901a\uff0c\u56e0\u6b64\u5b58\u5728\u79ef\u6781\u7684\u76f8\u4e92\u4ea4\u6d41&nbsp;\/&nbsp;\u76f8\u4e92\u4f5c\u7528\u3002(C)&nbsp;\u542b\u9aa8\u7684\u4eba\u4f53\u5173\u8282\u4f53\u5916\u6a21\u578b\uff0c\u5b58\u5728\u7ec6\u80de\u7c7b\u578b\u95f4\u76f8\u4e92\u4ea4\u6d41\u7684\u53ef\u80fd\u6027\uff0c\u4f46\u8fd9\u9650\u5236\u4e86\u7ec6\u80de\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u3002(B)&nbsp;\u672c\u7814\u7a76\u4e2d\u5f00\u53d1\u7684\u5171\u57f9\u517b\u6a21\u578b\uff0c\u7531\u5355\u4e00\u57f9\u517b\u3001\u5171\u57f9\u517b\u548c\u4f53\u5185\u4eba\u4f53\u5173\u8282\u7cfb\u7edf\u7684\u6bd4\u8f83\u7ec4\u6210\u3002(A)&nbsp;\u7ecf\u5178\u7684\u9759\u6001\u5355\u4e00\u57f9\u517b\u6a21\u578b<\/figcaption><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">2.\u00a0\u00a0\u00a0 \u5fae\u6d41\u63a7\u6280\u672f\u7684\u6838\u5fc3\u4f18\u52bf\u4e0e\u5b9e\u9a8c\u9a8c\u8bc1<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f20\u7edf OA \u7814\u7a76\u6a21\u578b\u5b58\u5728\u663e\u8457\u7f3a\u9677\uff1a\u5355\u57f9\u517b\u6a21\u578b\u65e0\u6cd5\u590d\u73b0\u5173\u8282\u5185\u9aa8\u3001\u8f6f\u9aa8\u3001\u6ed1\u819c\u7ec4\u7ec7\u7684\u7ec6\u80de\u95f4\u4ea4\u4e92\uff0c\u52a8\u7269\u6a21\u578b\u5219\u56e0\u751f\u7406\u5dee\u5f02\u5bfc\u81f4\u5b9e\u9a8c\u7ed3\u679c\u96be\u4ee5\u5411\u4eba\u4f53\u8f6c\u5316\u3002\u9488\u5bf9\u8fd9\u4e00\u95ee\u9898\uff0c\u7814\u7a76\u56e2\u961f\u4ee5<strong>\u5fae\u6d41\u63a7\u82af\u7247\u5728\u9aa8\u5173\u8282\u708e\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u5e94\u7528<\/strong>\u4e3a\u6838\u5fc3\u76ee\u6807\uff0c\u5f00\u53d1\u4e86\u591a\u7ec6\u80de\u5171\u57f9\u517b\u7cfb\u7edf\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8be5\u7cfb\u7edf\u91c7\u7528<a href=\"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/413\/pdms\u82af\u7247\u52a0\u5de5\u8bbe\u5907\/\"> PDMS \u82af\u7247\u52a0\u5de5<\/a>\u6280\u672f\u4e0e <a href=\"https:\/\/www.dxfluidics.com\/en\/microfluidic-device\/mems\u8bbe\u5907\/\">MEMS<\/a> \u5de5\u827a\uff0c\u57fa\u4e8e \u03bc-Slide I Luer \u5fae\u6d41\u63a7\u82af\u7247\uff0c\u6210\u529f\u6574\u5408\u4eba\u7c7b\u6210\u9aa8\u7ec6\u80de\uff08\u63a5\u79cd\u5bc6\u5ea6 40,000 cells\/cm\u00b2\uff09\u3001\u8f6f\u9aa8\u7ec6\u80de\uff0880,000 cells\/cm\u00b2\uff09\u3001\u6210\u7ea4\u7ef4\u7ec6\u80de\uff08\u66ff\u4ee3\u6ed1\u819c\u6210\u7ea4\u7ef4\u7ec6\u80de\uff09\u53ca\u5de8\u566c\u7ec6\u80de\uff08M0 \u9759\u606f\u6001\u3001M1 \u4fc3\u708e\u6001\uff09\uff0c\u5b9e\u73b0\u4e86\u53ef\u63a7\u6d41\u52a8\u73af\u5883\u4e0b\u7684\u7ec6\u80de\u5171\u57f9\u517b\u3002\u4e3a\u7cbe\u51c6\u590d\u73b0 OA \u708e\u75c7\u5fae\u73af\u5883\uff0c\u7814\u7a76\u901a\u8fc7\u5411\u57f9\u517b\u57fa\u6dfb\u52a0 IFN-\u03b3 \u4e0e\u8102\u591a\u7cd6\uff08LPS\uff09\uff0c\u8bf1\u5bfc M0 \u5de8\u566c\u7ec6\u80de\u5411 M1 \u8868\u578b\u5206\u5316\uff0c\u540c\u65f6\u5229\u7528\u6d41\u4f53\u6d41\u52a8\u5b9e\u73b0\u7ec6\u80de\u95f4\u65c1\u5206\u6ccc\u4fe1\u53f7\u4f20\u9012 \u2014\u2014 \u8fd9\u4e00\u8bbe\u8ba1\u8f83\u4f20\u7edf\u9759\u6001\u57f9\u517b\u66f4\u8d34\u8fd1\u4f53\u5185\u5173\u8282\u7684\u591a\u7ec4\u7ec7\u4ea4\u4e92\u7279\u6027\uff0c\u4e14\u91c7\u7528\u60a3\u8005\u6765\u6e90\u539f\u4ee3\u7ec6\u80de\uff08\u975e iPSCs\uff09\uff0c\u6709\u6548\u907f\u514d\u4e86\u5e72\u7ec6\u80de\u5206\u5316\u4e0d\u5747\u5bfc\u81f4\u7684\u8868\u578b\u504f\u5dee\uff0c\u663e\u8457\u63d0\u5347\u75be\u75c5\u6a21\u62df\u51c6\u786e\u6027\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"554\" height=\"360\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72472-4.png\" alt=\"\" class=\"wp-image-4636\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72472-4.png 554w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72472-4-18x12.png 18w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><figcaption class=\"wp-element-caption\">\u75be\u75c5\u6a21\u578b\u5f00\u53d1\u65b9\u6cd5\u3002(A)&nbsp;\u4e00\u7ec4\u65b9\u6cd5\u4f9d\u8d56\u6d41\u901f\uff0c\u6216\u5c06\u673a\u68b0\u529b\/\u6d41\u4f53\u526a\u5207\u5e94\u529b\u4f5c\u4e3a\u5bf9\u7ec6\u80de\u7684\u523a\u6fc0\u65b9\u6cd5\u3002(B)&nbsp;\u708e\u6027\u7ec6\u80de\u56e0\u5b50\uff0c\u5982\u767d\u7ec6\u80de\u4ecb\u7d20\u6216\u5176\u4ed6\u523a\u6fc0\u7269\uff0c\u76f4\u63a5\u4f5c\u7528\u4e8e\u7ec6\u80de\u4ee5\u8bf1\u5bfc\u75be\u75c5\u72b6\u6001\u3002(C)&nbsp;\u7269\u7406\u523a\u6fc0\u6216\u5fae\u73af\u5883\uff08\u4f8b\u5982\u5404\u79cd\u652f\u67b6\uff09\uff0c\u65e8\u5728\u5f15\u5bfc\u5e76\u5f15\u53d1\u7ec6\u80de\u4ea7\u751f\u5177\u6709\u75be\u75c5\u7279\u5f81\u7684\u53cd\u5e94\u3002(D)&nbsp;\u4e3a\u6a21\u62df\u708e\u75c7\u6027\u75be\u75c5\u4e2d\u7684\u60c5\u51b5\uff0c\u8be5\u7cfb\u7edf\u7528\u514d\u75ab\u7ec6\u80de\uff08\u5305\u62ec\u5de8\u566c\u7ec6\u80de\uff09\u8fdb\u884c\u5904\u7406\uff0c\u5de8\u566c\u7ec6\u80de\u523a\u6fc0\u708e\u6027\u7ec6\u80de\u56e0\u5b50\u7684\u5206\u6ccc\u3002<\/figcaption><\/figure>\n<\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"554\" height=\"292\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72473-4.png\" alt=\"\" class=\"wp-image-4637\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72473-4.png 554w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72473-4-18x9.png 18w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><figcaption class=\"wp-element-caption\">\u5b9e\u9a8c\u88c5\u7f6e\u4e0e\u5de5\u4f5c\u6d41\u7a0b\u3002(A)&nbsp;\u793a\u610f\u56fe\uff0c(B)&nbsp;\u7f6e\u4e8e\u57f9\u517b\u7bb1\u5185\u7684\u5b9e\u9a8c\u88c5\u7f6e\u7167\u7247\uff0c\u5728\u5b9e\u9a8c\u671f\u95f4\uff0c\u5fae\u6d41\u63a7\u7cfb\u7edf\u5728\u53ef\u63a7\u6761\u4ef6\u4e0b\u8fd0\u884c\u3002<\/figcaption><\/figure>\n<\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"554\" height=\"716\" src=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72474-4.png\" alt=\"\" class=\"wp-image-4638\" srcset=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72474-4.png 554w, https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/08\/\u56fe\u72474-4-9x12.png 9w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><figcaption class=\"wp-element-caption\">\u5728\u5065\u5eb7\u548c\u75be\u75c5\u6a21\u578b\u4e2d\uff0c\u5171\u57f9\u517b24\u5c0f\u65f6\u65f6\u7ec6\u80de\u6d3b\u529b\u57fa\u672c\u4fdd\u6301\u4e0d\u53d8\u3002(A)&nbsp;\u6d3b\u7ec6\u80de\uff08\u7eff\u8272\uff09\u548c\u6b7b\u7ec6\u80de\uff08\u767d\u8272\uff09\u7ec6\u80de\u6838\u7684\u4ee3\u8868\u6027\u56fe\u50cf\u3002(B)&nbsp;\u5b9a\u91cf\u7ec6\u80de\u6d3b\u529b\u6570\u636e\uff1a(i)&nbsp;\u5355\u4e00\u57f9\u517b\u3001\u5065\u5eb7\u5171\u57f9\u517b\u3001\u75be\u75c5\u5171\u57f9\u517b\u6a21\u578b\u53ca\u6b7b\u4ea1\u5bf9\u7167\u7ec4\u4e2d\u6240\u6709\u7ec6\u80de\u7c7b\u578b\u7684\u6c47\u603b\u6570\u636e\uff1b(ii)&nbsp;\u6210\u9aa8\u7ec6\u80de\uff08HOB\uff09\uff1b(iii)&nbsp;\u8f6f\u9aa8\u7ec6\u80de\uff08HCH\uff09\uff1b(iv)&nbsp;\u6210\u7ea4\u7ef4\u7ec6\u80de\uff08HDF\uff09\uff1b(v)&nbsp;\u9759\u6b62\uff08M0\uff09\u5de8\u566c\u7ec6\u80de\uff0c\u5373\u5065\u5eb7\u6a21\u578b\uff1b\u4ee5\u53ca(vi)&nbsp;\u4fc3\u708e\uff08M1\uff09\u5de8\u566c\u7ec6\u80de\uff0c\u5373\u75be\u75c5\u6a21\u578b\u3002\u6570\u636e\u4e3a\u5e73\u5747\u503c\u00b195%\u7f6e\u4fe1\u533a\u95f4\u3002\\(*p&lt;0.05\\)&nbsp;\\(**p&lt;0.01\\)&nbsp;\u2605**\u2605&nbsp;\\(p&lt;0.0001\\)&nbsp;\u6bd4\u4f8b\u5c3a\uff1a200\u5fae\u7c73\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5fae\u6d41\u63a7\u82af\u7247\u5728\u9aa8\u5173\u8282\u708e\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u5e94\u7528<\/strong>\u4e4b\u6240\u4ee5\u5177\u5907\u521b\u65b0\u6027\uff0c\u6838\u5fc3\u6e90\u4e8e\u4e09\u5927\u6280\u672f\u4f18\u52bf\uff1a<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u7cbe\u51c6\u7a7a\u95f4\u5206\u5e03<\/strong>\uff1a\u901a\u8fc7 PDMS \u952e\u5408\u5bf9\u51c6\u5e73\u53f0\uff0c\u4f7f\u6210\u9aa8\u7ec6\u80de\u3001\u8f6f\u9aa8\u7ec6\u80de\u7b49\u5728\u5404\u81ea\u5fae\u901a\u9053\u5185\u6709\u5e8f\u63a5\u79cd\uff0c\u65e2\u4fdd\u969c\u7ec6\u80de\u7279\u5f02\u6027\u751f\u957f\u73af\u5883\uff0c\u53c8\u4e3a\u7ec6\u80de\u95f4\u4ea4\u4e92\u63d0\u4f9b\u7ed3\u6784\u57fa\u7840\uff1b<\/li>\n\n\n\n<li><strong>\u4eff\u751f\u673a\u68b0\u523a\u6fc0<\/strong>\uff1a\u91c7\u7528 Masterflex\u00ae <a href=\"https:\/\/www.dxfluidics.com\/en\/product\/microfluidic-device\/sample-introduction-instrument\/peristaltic-pump\/4387\/\u8815\u52a8\u6cf5\/\">peristaltic pump<\/a>\u8c03\u63a7 0.05 dyn\/cm\u00b2 \u7684\u6d41\u4f53\u526a\u5207\u5e94\u529b\uff0c\u6a21\u62df\u5173\u8282\u6ed1\u6db2\u6d41\u52a8\u5bf9\u7ec6\u80de\u7684\u673a\u68b0\u523a\u6fc0\uff0c\u540c\u65f6\u4fc3\u8fdb\u8425\u517b\u4ea4\u6362\u4e0e\u4ee3\u8c22\u7269\u6392\u51fa\uff0c\u89e3\u51b3\u9759\u6001\u57f9\u517b\u4e2d \u201c\u8425\u517b\u532e\u4e4f\u3001\u4ee3\u8c22\u5806\u79ef\u201d \u95ee\u9898\uff1b<\/li>\n\n\n\n<li><strong>\u591a\u7ef4\u5ea6\u8bc4\u4f30\u4f53\u7cfb<\/strong>\uff1a\u7ed3\u5408 NucBlue\u2122\/NucGreen\u2122\u6d3b\u6b7b\u7ec6\u80de\u67d3\u8272\u3001PrestoBlue\u2122\u4ee3\u8c22\u6d3b\u6027\u68c0\u6d4b\u53ca LDH \u7ec6\u80de\u6bd2\u6027 assay\uff0c\u5168\u9762\u9a8c\u8bc1\u6a21\u578b\u7a33\u5b9a\u6027\u3002<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b9e\u9a8c\u6570\u636e\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u6a21\u578b\u53ef\u9760\u6027\uff1a\u5171\u57f9\u517b 24 \u5c0f\u65f6\u540e\uff0c\u5065\u5eb7\u6a21\u578b\u4e0e\u75be\u75c5\u6a21\u578b\u7684\u7ec6\u80de\u5b58\u6d3b\u7387\u5206\u522b\u8fbe 83.9%\u00b114%\u300183.3%\u00b112%\uff0c\u4e0e\u5355\u57f9\u517b\uff0893.3%\u00b14%\uff09\u65e0\u663e\u8457\u5dee\u5f02\uff0c\u4e14 LDH \u91ca\u653e\u91cf\u672a\u5347\u9ad8\uff0c\u8868\u660e\u7ec6\u80de\u819c\u5b8c\u6574\u6027\u672a\u53d7\u7ec6\u80de\u6bd2\u6027\u5f71\u54cd\uff1b\u66f4\u5173\u952e\u7684\u662f\uff0c\u5171\u57f9\u517b\u7ec6\u80de\u4ee3\u8c22\u6d3b\u6027\u663e\u8457\u589e\u5f3a \u2014\u2014 \u5065\u5eb7\u6a21\u578b\u3001\u75be\u75c5\u6a21\u578b\u4ee3\u8c22\u6c34\u5e73\u5206\u522b\u662f\u5355\u57f9\u517b\u7684 5.9\u00b13.2 \u500d\u30015.3\u00b13.4 \u500d\uff0c\u76f4\u63a5\u8bc1\u5b9e\u7ec6\u80de\u95f4\u901a\u8baf\u5bf9\u7ef4\u6301\u751f\u7406\u529f\u80fd\u7684\u79ef\u6781\u4f5c\u7528\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">1. \u5f15\u7528 Ibidi \u516c\u53f8 \u03bc-Slide I Luer \u82af\u7247\u6280\u672f\u8bf4\u660e\u9875\u9762\uff0c\u94fe\u63a5\uff1a<a href=\"https:\/\/ibidi.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/ibidi.com\/<\/a>\u00b5-slide-i-luer.html\uff1b<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2. \u5f15\u7528 WHO \u5173\u4e8e\u9aa8\u5173\u8282\u708e\u7684\u75be\u75c5\u5b9a\u4e49\u9875\u9762\uff0c\u94fe\u63a5\uff1a<a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/osteoarthritis\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/osteoarthritis<\/a>\uff1b<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">3. \u5f15\u7528 Nature Reviews Rheumatology \u5173\u4e8e OA \u4f53\u5916\u6a21\u578b\u7684\u7efc\u8ff0\uff0c\u94fe\u63a5\uff1a<a href=\"https:\/\/www.nature.com\/nrrheum\/articles?type=review-article\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.nature.com\/nrrheum\/articles?type=review-article<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3.\u00a0\u00a0\u00a0 \u5173\u952e\u6280\u672f\u652f\u6491\u4e0e\u52a0\u5de5\u5de5\u827a<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5fae\u6d41\u63a7\u82af\u7247\u5728\u9aa8\u5173\u8282\u708e\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u5e94\u7528<\/strong>\u4f9d\u8d56\u7cbe\u5bc6\u7684\u82af\u7247\u52a0\u5de5\u4e0e\u7ec6\u80de\u4f53\u7cfb\u8bbe\u8ba1\uff1a<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u82af\u7247\u52a0\u5de5<\/strong>\uff1a\u4ee5 PDMS \u4e3a\u57fa\u6750\uff0c\u901a\u8fc7\u5149\u523b\u80f6\u6a21\u5177\u5236\u5907\u4e0e PDMS \u6d47\u7b51\u5de5\u827a\u5b9e\u73b0\u5fae\u901a\u9053\u7cbe\u51c6\u6210\u578b\uff0c\u901a\u9053\u5c3a\u5bf8\u4e0e\u7ec6\u80de\u63a5\u79cd\u5bc6\u5ea6\u5339\u914d\uff08\u5982\u8f6f\u9aa8\u7ec6\u80de 80,000 cells\/cm\u00b2\uff09\uff0c\u786e\u4fdd\u7ec6\u80de\u8d34\u58c1\u4e0e\u751f\u957f\u7a7a\u95f4\uff1b\u7ed3\u5408 MEMS \u6280\u672f\u5b8c\u6210\u5fae\u901a\u9053\u5bc6\u5c01\u4e0e\u6d41\u4f53\u63a5\u53e3\u8bbe\u8ba1\uff0c\u914d\u5408\u8815\u52a8\u6cf5\u5f62\u6210\u95ed\u73af\u6d41\u52a8\u7cfb\u7edf\uff0c\u6ee1\u8db3 24 \u5c0f\u65f6\u9759\u6001\u5171\u57f9\u517b\u4e0e\u52a8\u6001\u8425\u517b\u4ea4\u6362\u7684\u53cc\u91cd\u9700\u6c42\u3002<\/li>\n\n\n\n<li><strong>\u7ec6\u80de\u4f53\u7cfb\u4f18\u5316<\/strong>\uff1a\u91c7\u7528\u4eba\u771f\u76ae\u6210\u7ea4\u7ef4\u7ec6\u80de\u66ff\u4ee3\u6ed1\u819c\u6210\u7ea4\u7ef4\u7ec6\u80de\uff0c\u901a\u8fc7\u5171\u57f9\u517b\u65c1\u5206\u6ccc\u4fe1\u53f7\u5f25\u8865\u529f\u80fd\u5dee\u5f02\uff1b\u5de8\u566c\u7ec6\u80de\u7531 THP-1 \u5355\u6838\u7ec6\u80de\u7ecf PMA \u8bf1\u5bfc\u4e3a M0 \u8868\u578b\u540e\uff0c\u518d\u7528 IFN-\u03b3+LPS \u5904\u7406\u83b7\u5f97 M1 \u8868\u578b\uff0c\u6807\u51c6\u5316\u6d41\u7a0b\u786e\u4fdd\u708e\u75c7\u6a21\u578b\u7a33\u5b9a\u6027\u3002<\/li>\n<\/ol>\n\n\n\n<h2 class=\"wp-block-heading\">4.&nbsp;&nbsp;&nbsp; \u5e94\u7528\u524d\u666f\u4e0e\u6280\u672f\u62d3\u5c55<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f53\u524d<strong>\u5fae\u6d41\u63a7\u82af\u7247\u5728\u9aa8\u5173\u8282\u708e\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u5e94\u7528<\/strong>\u5df2\u5c55\u73b0\u4e24\u5927\u6838\u5fc3\u4ef7\u503c\uff1a\u4e00\u662f\u4f5c\u4e3a\u75c5\u7406\u7814\u7a76\u5e73\u53f0\uff0c\u53ef\u89e3\u6790 M1 \u5de8\u566c\u7ec6\u80de\u5206\u6ccc\u7684\u708e\u75c7\u56e0\u5b50\u5bf9\u8f6f\u9aa8\u964d\u89e3\u7684\u8c03\u63a7\u673a\u5236\uff0c\u63a2\u7d22\u9aa8 &#8211; \u8f6f\u9aa8 &#8211; \u6ed1\u819c\u7684\u4ea4\u4e92\u75c5\u7406\u8fc7\u7a0b\uff1b\u4e8c\u662f\u4f5c\u4e3a\u836f\u7269\u7b5b\u9009\u5de5\u5177\uff0c\u901a\u8fc7\u6a21\u62df\u75be\u75c5\u72b6\u6001\u4e0b\u7684\u7ec6\u80de\u5e94\u7b54\uff0c\u8bc4\u4f30\u6297\u708e\u836f\u7269\u3001\u8f6f\u9aa8\u4fdd\u62a4\u5242\u7684 efficacy \u4e0e\u5b89\u5168\u6027\uff0c\u964d\u4f4e\u52a8\u7269\u5b9e\u9a8c\u6210\u672c\u4e0e\u7269\u79cd\u5dee\u5f02\u98ce\u9669\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672a\u6765\u6280\u672f\u4f18\u5316\u65b9\u5411\u5305\u62ec\uff1a\u7ec6\u80de\u5c42\u9762\u5f15\u5165\u80a5\u5927\u7ec6\u80de\u3001\u6d46\u7ec6\u80de\u5b8c\u5584\u708e\u75c7\u7f51\u7edc\uff1b\u73af\u5883\u8c03\u63a7\u5c42\u9762\u901a\u8fc7\u6d41\u52a8\u901f\u7387\u8c03\u8282\u65bd\u52a0\u673a\u68b0\u5e94\u529b\uff0c\u6a21\u62df\u5173\u8282\u8fd0\u52a8\u523a\u6fc0\uff1b\u52a0\u5de5\u5de5\u827a\u4e0a\u7ed3\u5408 <a href=\"https:\/\/www.dxfluidics.com\/en\/microfluidic-chip\/organ-chip\/\">3D Cell Culture Chip<\/a>\u4e0e\u7ec6\u80de\u5916\u57fa\u8d28\uff08ECM\uff09\uff0c\u63d0\u5347\u5fae\u73af\u5883\u4eff\u751f\u5ea6\uff1b\u66f4\u53ef\u4e0e\u5668\u5b98\u82af\u7247\u5e73\u53f0\u878d\u5408\uff0c\u6784\u5efa \u201c\u5173\u8282 &#8211; \u4ee3\u8c22\u5668\u5b98\u201d \u8054\u52a8\u6a21\u578b\uff0c\u63a2\u7d22 OA \u4e0e\u5168\u8eab\u4ee3\u8c22\u7684\u5173\u8054\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5728\u9aa8\u5173\u8282\u708e\uff08OA\uff09\u7814\u7a76\u4e2d\uff0c\u4f20\u7edf\u5355\u57f9\u517b\u6a21\u578b\u56e0\u7f3a\u4e4f\u7ec6\u80de\u95f4\u901a\u8baf\u3001\u52a8\u7269\u6a21\u578b\u56e0\u7269\u79cd\u5dee\u5f02\u96be\u4ee5\u7cbe\u51c6\u6a21\u62df\u4f53\u5185\u5173\u8282\u5fae\u73af\u5883\uff0c\u6210\u4e3a\u5236 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":4635,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","footnotes":""},"categories":[5],"tags":[],"class_list":["post-4634","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-information"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u5fae\u6d41\u63a7\u82af\u7247\u5728\u9aa8\u5173\u8282\u708e\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u5e94\u7528 | \u7814\u7a76\u8fdb\u5c55\u89e3\u6790 - \u9876\u65ed\u5fae\u63a7<\/title>\n<meta name=\"description\" content=\"\u672c\u6587\u805a\u7126\u5fae\u6d41\u63a7\u82af\u7247\u5728\u9aa8\u5173\u8282\u708e\u5173\u8282\u708e\u75c7\u6a21\u578b\u4e2d\u7684\u5e94\u7528\uff0c\u89e3\u6790\u5176\u901a\u8fc7 PDMS\/MEMS 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