{"id":4589,"date":"2025-08-19T09:17:51","date_gmt":"2025-08-19T01:17:51","guid":{"rendered":"https:\/\/www.dxfluidics.com\/?p=4589"},"modified":"2025-08-19T09:17:52","modified_gmt":"2025-08-19T01:17:52","slug":"%e5%9f%ba%e4%ba%8e%e5%be%ae%e6%b5%81%e4%bd%93%e8%8a%af%e7%89%87%e7%9a%84%e5%bf%ab%e9%80%9f%e6%8a%97%e8%8f%8c%e8%8d%af%e6%95%8f%e6%a3%80%e6%b5%8b%e6%8a%80%e6%9c%af%e8%a7%a3%e6%9e%90","status":"publish","type":"post","link":"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/4589\/%e5%9f%ba%e4%ba%8e%e5%be%ae%e6%b5%81%e4%bd%93%e8%8a%af%e7%89%87%e7%9a%84%e5%bf%ab%e9%80%9f%e6%8a%97%e8%8f%8c%e8%8d%af%e6%95%8f%e6%a3%80%e6%b5%8b%e6%8a%80%e6%9c%af%e8%a7%a3%e6%9e%90\/","title":{"rendered":"\u57fa\u4e8e\u5fae\u6d41\u4f53\u82af\u7247\u7684\u5feb\u901f\u6297\u83cc\u836f\u654f\u68c0\u6d4b\u6280\u672f\u89e3\u6790"},"content":{"rendered":"

\u53c2\u8003\u6587\u732e\uff1ahttps:\/\/doi.org\/10.1038\/s41378-025-00938-y<\/p>\n\n\n\n

1.    \u5fae\u6d41\u4f53\u82af\u7247\u7684\u8bbe\u8ba1\u4e0e\u5236\u5907\u5de5\u827a<\/h2>\n\n\n\n

SDFAST\uff08Self Dilution for Faster Antimicrobial Susceptibility Testing\uff09\u4f5c\u4e3a\u4e00\u79cd\u65b0\u578b\u5fae\u6d41\u4f53\u82af\u7247\u7cfb\u7edf\uff0c\u5176\u6838\u5fc3\u8bbe\u8ba1\u91c7\u7528\u4e86\u53cc\u5c42 SlipChip \u7ed3\u6784\uff0c\u7531\u9876\u5c42\u82af\u7247\u4e0e\u5e95\u5c42\u82af\u7247\u7ec4\u6210\uff0c\u901a\u8fc7\u7cbe\u51c6\u5bf9\u9f50\u5b9e\u73b0\u6d41\u4f53\u63a7\u5236\u3002\u8be5\u82af\u7247\u9009\u7528 3mm \u539a\u7684\u805a\u7532\u57fa\u4e19\u70ef\u9178\u7532\u916f\uff08PMMA\uff09\u4f5c\u4e3a\u57fa\u6750\uff0c\u5229\u7528\u5fae\u94e3\u524a\u6280\u672f\u66ff\u4ee3\u4f20\u7edf\u5316\u5b66\u8680\u523b\u5de5\u827a\uff0c\u4e0d\u4ec5\u5c06\u5355\u5957\u82af\u7247\u7684\u5236\u5907\u65f6\u95f4\u7f29\u77ed\u81f3 30 \u5206\u949f\u4ee5\u5185\uff0c\u8fd8\u80fd\u901a\u8fc7\u8ba1\u7b97\u673a\u7cfb\u7edf\u7075\u6d3b\u8c03\u6574\u52a0\u5de5\u53c2\u6570\uff0c\u6781\u5927\u63d0\u5347\u4e86\u5de5\u827a\u7684\u7075\u6d3b\u6027\u3002\u8fd9\u79cd\u52a0\u5de5\u65b9\u5f0f\u4e0e MEMS \u52a0\u5de5\u6280\u672f\u4e2d\u7684\u5fae\u7eb3\u5236\u9020\u7406\u5ff5\u76f8\u5951\u5408\uff0c\u901a\u8fc7 2.5D \u76f2\u94e3\u529f\u80fd\u5b9a\u4e49\u5404\u7ec4\u4ef6\u9ad8\u5ea6\uff0c\u914d\u5408 0.9mm \u87ba\u65cb\u94bb\u5177\u4e0e 0.5mm \u7acb\u94e3\u5200\u5b8c\u6210 inlet\u3001outlet \u53ca\u5fae\u4e95\u7ed3\u6784\u7684\u52a0\u5de5\uff0c\u6700\u7ec8\u7ecf\u53bb\u79bb\u5b50\u6c34\u4e0e\u4e59\u9187\u6e05\u6d17\u5b9e\u73b0\u8868\u9762\u51c0\u5316\u3002<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

 SDFAST\u4e0e\u5f53\u524d\u65b9\u6cd5\uff08\u5982\u7eb8\u7247\u6269\u6563\u6cd5\uff09\u7684\u5bf9\u6bd4\u793a\u610f\u56fe\u3002\u5f53\u524d\u65b9\u6cd5\u7684\u4e3b\u8981\u7f3a\u70b9\u4e4b\u4e00\u662f\u68c0\u6d4b\u6301\u7eed\u65f6\u95f4\u957f\uff0c\u5c24\u5176\u662f\u57f9\u517b\u9700\u898120\u591a\u4e2a\u5c0f\u65f6\u3002\u7136\u800c\uff0c\u5728SDFAST\u4e2d\uff0c\u57f9\u517b\u65f6\u95f4\u7f29\u77ed\u81f34 – 6\u5c0f\u65f6\uff0c\u8fd9\u4f7f\u5f97\u533b\u751f\u80fd\u591f\u5728\u4e00\u5929\u5185\u5feb\u901f\u83b7\u5f97\u6297\u751f\u7d20\u654f\u611f\u6027\u8bd5\u9a8c\uff08AST\uff09\u7ed3\u679c\uff0c\u5e76\u4e3a\u60a3\u8005\u5f00\u51fa\u76f8\u5e94\u7684\u6297\u751f\u7d20\u3002\u5728\u8be5\u793a\u610f\u56fe\u4e2d\uff0c\u5c55\u793a\u4e86SDFAST\u7684\u4e00\u90e8\u5206\uff0c\u4ee5\u8bf4\u660e\u5982\u4f55\u8fdb\u884c\u4e00\u79cd\u7ec6\u83cc – \u6297\u751f\u7d20\u7ec4\u5408\u7684\u6d4b\u8bd5\u3002<\/p>\n\n\n\n

\u5728\u7ed3\u6784\u8bbe\u8ba1\u4e0a\uff0c\u9876\u5c42\u82af\u7247\u5305\u542b\u4f53\u79ef\u4f9d\u6b21\u51cf\u534a\u7684\u5fae\u4e95\u9635\u5217\uff0c\u5e95\u5c42\u82af\u7247\u5219\u91c7\u7528\u6052\u5b9a\u4f53\u79ef\u7684\u7eb3\u7c73\u58c1\u7ed3\u6784\uff0c\u901a\u8fc7\u6ed1\u52a8\u9519\u4f4d\u5b9e\u73b0\u6297\u751f\u7d20\u7684\u68af\u5ea6\u7a00\u91ca\u3002\u8fd9\u79cd\u8bbe\u8ba1\u5de7\u5999\u6574\u5408\u4e86\u5fae\u6d41\u63a7\u82af\u7247\u6a21\u5177\u7684\u7cbe\u5bc6\u5236\u9020\u8981\u6c42\uff0c\u5176 840nL \u81f3 6.563nL \u7684\u4f53\u79ef\u68af\u5ea6\u8bbe\u7f6e\uff0c\u4e3a\u540e\u7eed\u7684\u6d53\u5ea6\u68af\u5ea6\u751f\u6210\u5960\u5b9a\u4e86\u7269\u7406\u57fa\u7840\u3002\u82af\u7247\u8868\u9762\u7ecf\u6c1f\u70f7\u57fa\u7845\u70f7\u5904\u7406\u5f62\u6210\u758f\u6c34\u5c42\uff0c\u5e76\u6dfb\u52a0 1% \u8868\u9762\u6d3b\u6027\u5242\u7684 FC-40 \u6eb6\u6db2\u5b9e\u73b0\u5bc6\u5c01\uff0c\u6709\u6548\u89e3\u51b3\u4e86\u5fae\u6d41\u4f53\u7cfb\u7edf\u4e2d\u5e38\u89c1\u7684\u84b8\u53d1\u4e0e\u6cc4\u6f0f\u95ee\u9898\uff0c\u8fd9\u4e00\u5de5\u827a\u4e0e PDMS \u82af\u7247\u52a0\u5de5\u4e2d\u5e38\u7528\u7684\u8868\u9762\u4fee\u9970\u6280\u672f\u5f02\u66f2\u540c\u5de5\u3002<\/p>\n\n\n\n

2.    \u5fae\u6d41\u4f53\u82af\u7247\u7684\u5de5\u4f5c\u539f\u7406\u4e0e\u6838\u5fc3\u6280\u672f<\/h2>\n\n\n\n

SDFAST \u7cfb\u7edf\u7684\u5de5\u4f5c\u6d41\u7a0b\u5206\u4e3a\u52a0\u8f7d\u3001\u6db2\u6ef4\u5f62\u6210\u4e0e\u6df7\u5408\u4e09\u4e2a\u5173\u952e\u9636\u6bb5\uff0c\u5b8c\u7f8e\u5c55\u73b0\u4e86\u5fae\u6d41\u63a7\u6280\u672f\u7684\u7cbe\u51c6\u64cd\u63a7\u7279\u6027\u3002\u5728\u52a0\u8f7d\u9636\u6bb5\uff0c\u4e0a\u4e0b\u82af\u7247\u5bf9\u9f50\u5f62\u6210\u6d41\u4f53\u901a\u9053\uff0c\u901a\u8fc7\u5fae\u91cf\u79fb\u6db2\u5668\u5c06\u7ec6\u83cc\u60ac\u6db2\u4e0e\u6297\u751f\u7d20\u6eb6\u6db2\u6ce8\u5165\uff0c\u591a\u4f59\u6db2\u4f53\u7ecf\u51fa\u53e3\u6392\u51fa\u4ee5\u5e73\u8861\u538b\u529b\u3002\u8fd9\u4e00\u8fc7\u7a0b\u7c7b\u4f3c\u4e8e PDMS \u82af\u7247\u52a0\u5de5\u4e2d\u5e38\u89c1\u7684\u6d41\u4f53\u704c\u6ce8\u64cd\u4f5c\uff0c\u4f46\u5176\u521b\u65b0\u70b9\u5728\u4e8e\u901a\u8fc7\u5355\u6b21\u6ed1\u52a8\u5b9e\u73b0\u53cc\u91cd\u529f\u80fd\uff1a\u63a8\u52a8\u9876\u5c42\u82af\u7247\u9996\u5148\u5f62\u6210\u72ec\u7acb\u6db2\u6ef4\u5e76\u65ad\u5f00\u8fdb\u51fa\u53e3\u8fde\u63a5\uff0c\u5229\u7528\u9876\u5c42\u5fae\u4e95\u7684\u4f53\u79ef\u68af\u5ea6\u5b8c\u6210\u6297\u751f\u7d20\u7684\u5feb\u901f\u81ea\u7a00\u91ca\uff0c\u968f\u540e\u8fdb\u4e00\u6b65\u6ed1\u52a8\u4f7f\u4e0a\u4e0b\u6db2\u6ef4\u878d\u5408\uff0c\u5b9e\u73b0\u7ec6\u83cc\u4e0e\u4e0d\u540c\u6d53\u5ea6\u6297\u751f\u7d20\u7684\u5145\u5206\u53cd\u5e94\u3002<\/p>\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

SDFAST\u82af\u7247\u5de5\u4f5c\u539f\u7406\u3002a \u8be5\u88c5\u7f6e\u5de5\u4f5c\u539f\u7406\u793a\u610f\u56fe\u3002\u7ea2\u8272\u4ee3\u8868\u7ec6\u83cc\uff0c\u7eff\u8272\u4ee3\u8868\u6297\u751f\u7d20\u3002\u7d2b\u8272\u6846\u5185\u90e8\u5206\u653e\u5927\u4ee5\u5c55\u793a\u6bcf\u4e2a\u6b65\u9aa4\u7684\u7ec6\u8282\uff0c\u5e76\u5c55\u793a\u6bcf\u4e2a\u6b65\u9aa4\u4e2d\u5f69\u8272\u67d3\u6599\u56fe\u6848\u7684\u7167\u7247\u30023D\u6a21\u578b\u4f7f\u7528Blender 4.1\u6784\u5efa\u3002b \u73af\u4e19\u6c99\u661f\uff08CIP\uff09\u4e0e\u9c8d\u66fc\u4e0d\u52a8\u6746\u83cc\u6df7\u5408\u7684SDFAST\u7ed3\u679c\u793a\u4f8b\uff0c\u91c7\u7528WST – 8\u68c0\u6d4b\u6cd5\u3002\u5728\\(5th\\)\u7eb3\u7c73\u5b54\u5904\u89c2\u5bdf\u5230\u989c\u8272\u5f3a\u5ea6\u7684\u7a81\u7136\u53d8\u5316\uff08\u4ece\u65e0\u8272\u53d8\u4e3a\u6a59\u8272\uff09\uff0c\u8868\u660e\u6b64\u5904\u4e3a\u6700\u4f4e\u6291\u83cc\u6d53\u5ea6\uff08MIC\uff09\u3002c WST – 8\u68c0\u6d4b\u6cd5\u7684\u989c\u8272\u56fe\u6848\u7167\u7247<\/p>\n\n\n\n

\u8be5\u7cfb\u7edf\u91c7\u7528\u6c34\u6eb6\u6027\u56db\u5511\u76d0 – 8\uff08WST-8\uff09\u663e\u8272\u6cd5\u4f5c\u4e3a\u68c0\u6d4b\u624b\u6bb5\uff0c\u901a\u8fc7\u989c\u8272\u5f3a\u5ea6\u53d8\u5316\u5224\u65ad\u7ec6\u83cc\u751f\u957f\u72b6\u6001\u3002\u5f53\u6297\u751f\u7d20\u6d53\u5ea6\u4f4e\u4e8e\u6700\u4f4e\u6291\u83cc\u6d53\u5ea6\uff08MIC\uff09\u65f6\uff0c\u7ec6\u83cc\u4ee3\u8c22\u6d3b\u52a8\u4f7f WST-8 \u4ea7\u751f\u6a59\u8272\u663e\u8272\u53cd\u5e94\uff0c\u8fd9\u79cd\u989c\u8272\u53d8\u5316\u53ef\u901a\u8fc7 ImageJ \u8f6f\u4ef6\u8fdb\u884c\u91cf\u5316\u5206\u6790\uff0c\u8ba1\u7b97\u6821\u6b63\u540e\u7684\u989c\u8272\u5f3a\u5ea6\u503c\u3002\u5b9e\u9a8c\u6570\u636e\u663e\u793a\uff0c\u5728 4 – 6 \u5c0f\u65f6\u5b75\u80b2\u540e\uff0c\u989c\u8272\u5f3a\u5ea6\u4f1a\u51fa\u73b0 abrupt \u53d8\u5316\uff0c\u8fd9\u4e00\u7279\u5f81\u6210\u4e3a MIC \u5224\u65ad\u7684\u76f4\u89c2\u4f9d\u636e\uff0c\u76f8\u6bd4\u4f20\u7edf\u6d4a\u5ea6\u6cd5\u66f4\u6613\u533a\u5206\u5fae\u5c0f\u6d53\u5ea6\u5dee\u5f02\uff08\u22641\u03bcg\/mL\uff09\u7684\u6837\u672c\u3002<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u7cfb\u7edf\u5185\u7a00\u91ca\u6240\u6d89\u53ca\u7684\u5c3a\u5bf8\u548c\u5b54\u3002a SDFAST\u8bbe\u5907\u7684\u7167\u7247\u3002\u8be5\u8bbe\u5907\u7531b \u9876\u90e8\u82af\u7247\u548cc \u5e95\u90e8\u82af\u7247\u7ec4\u6210\u3002\u7d2b\u8272\u6846\u7a81\u51fa\u663e\u793a\u4e86\u8d1f\u8d23\u7cfb\u7edf\u5185\u7a00\u91ca\u7684\u4e24\u6392\u5b54\uff0c\u5982\u56fe(d)\u6240\u793a\uff1a\u9876\u90e8\u82af\u7247\u7531\u4ece\u5de6\u5230\u53f3\u4f53\u79ef\u9010\u6e10\u51cf\u5c0f\u7684\u5b54\u7ec4\u6210\uff0c\u800c\u5e95\u90e8\u82af\u7247\u7531\u4f53\u79ef\u6052\u5b9a\u7684\u5b54\u7ec4\u6210\u3002\u6ed1\u52a8\u8fc7\u7a0b\u4e2d\uff0c\u9876\u90e8\u82af\u7247\u7684\u5b54\u5f62\u6210\u4f53\u79ef\u9010\u6e10\u51cf\u5c0f\u7684\u6db2\u6ef4\uff0c\u4ece\u800c\u7a00\u91ca\u6eb6\u6db2\u3002\u540c\u65f6\uff0c\u5e95\u90e8\u82af\u7247\u7684\u5b54\u5f62\u6210\u4f53\u79ef\u6052\u5b9a\u7684\u6db2\u6ef4\u3002\u6ed1\u52a8\u540e\uff0c\u4e24\u4e2a\u82af\u7247\u7684\u6db2\u6ef4\u5408\u5e76\u5728\u4e00\u8d77\u3002\u8fd9\u4e00\u8fc7\u7a0b\u5728\u56fe(e)\u4e2d\u8fdb\u4e00\u6b65\u5c55\u793a\uff0c\u5373\u4e24\u4e2a\u82af\u7247\u7684\u6a2a\u622a\u9762\u3002\u76f8\u5e94\u5c3a\u5bf8\u5217\u4e8e\u56fe(f)\u30023D\u6a21\u578b\u4f7f\u7528Blender 4.1\u6784\u5efa\u3002 <\/p>\n\n\n\n

\u5728\u7a00\u91ca\u673a\u5236\u4e0a\uff0c\u7cfb\u7edf\u901a\u8fc7\u516c\u5f0f C\u2080V\u2099 = C\u2099V\u209b \u8ba1\u7b97\u5404\u5fae\u4e95\u7684\u6297\u751f\u7d20\u6d53\u5ea6\uff0c\u5176\u4e2d V\u209b \u4e3a\u4e0a\u4e0b\u6db2\u6ef4\u878d\u5408\u540e\u7684\u603b\u4f53\u79ef\u3002\u4ee5\u521d\u59cb\u6d53\u5ea6 10\u03bcg\/mL \u7684\u6297\u751f\u7d20\u4e3a\u4f8b\uff0c\u7ecf\u7b2c\u4e00\u7ea7\u7a00\u91ca\u540e\u6d53\u5ea6\u964d\u81f3 5\u03bcg\/mL\uff0c\u7a00\u91ca\u56e0\u5b50 D\u2081 = 2\uff0c\u901a\u8fc7\u8fde\u7eed\u8ba1\u7b97\u53ef\u83b7\u5f97 8 \u4e2a\u68af\u5ea6\u7684\u7cbe\u786e\u6d53\u5ea6\uff0c\u8fd9\u4e00\u8fc7\u7a0b\u65e0\u9700\u5916\u90e8\u6cf5\u9600\u9a71\u52a8\uff0c\u5b8c\u5168\u4f9d\u8d56\u82af\u7247\u7ed3\u6784\u5b9e\u73b0\u81ea\u7a00\u91ca\uff0c\u4f53\u73b0\u4e86\u5fae\u6d41\u63a7\u82af\u7247\u8bbe\u8ba1\u4e2d \u201c\u7ed3\u6784\u5373\u529f\u80fd\u201d \u7684\u6838\u5fc3\u601d\u60f3\u3002<\/p>\n\n\n\n

3.    \u5728\u6297\u83cc\u836f\u654f\u68c0\u6d4b\u4e2d\u7684\u5e94\u7528\u4e0e\u6027\u80fd\u9a8c\u8bc1<\/h2>\n\n\n\n

1)    \u591a\u83cc\u79cd\u68c0\u6d4b\u80fd\u529b<\/h3>\n\n\n\n

SDFAST \u7cfb\u7edf\u5bf9\u4e34\u5e8a\u5e38\u89c1\u81f4\u75c5\u83cc\u5c55\u73b0\u51fa\u5e7f\u6cdb\u9002\u7528\u6027\u3002\u5728\u6a21\u578b\u6d4b\u8bd5\u4e2d\uff0c\u9488\u5bf9\u5927\u80a0\u6746\u83cc\uff08E. coli\uff09\u3001\u9c8d\u66fc\u4e0d\u52a8\u6746\u83cc\uff08A. baumannii\uff09\u548c\u80ba\u708e\u514b\u96f7\u4f2f\u83cc\uff08K. pneumoniae\uff09\uff0c\u5206\u522b\u91c7\u7528\u5934\u5b62\u4ed6\u5576\uff08CTZ\uff09\u3001\u73af\u4e19\u6c99\u661f\uff08CIP\uff09\u548c\u5de6\u6c27\u6c1f\u6c99\u661f\uff08LVX\uff09\u8fdb\u884c\u6d4b\u8bd5\uff0c\u7ed3\u679c\u663e\u793a\u5176 MIC \u503c\u4e0e\u4f20\u7edf\u8089\u6c64\u7a00\u91ca\u6cd5\u7684\u504f\u5dee\u5747\u5728 2 \u500d\u4ee5\u5185\u3002\u4f8b\u5982\uff0c\u9c8d\u66fc\u4e0d\u52a8\u6746\u83cc\u5bf9 CTZ \u7684 SDFAST \u68c0\u6d4b\u503c\u4e3a 55.6\u03bcg\/mL\uff0c\u800c\u4f20\u7edf\u65b9\u6cd5\u7ed3\u679c\u4e3a 62.5 – 125\u03bcg\/mL\uff0c\u8bc1\u660e\u8be5\u7cfb\u7edf\u5bf9\u9769\u5170\u6c0f\u9634\u6027\u83cc\u7684\u68c0\u6d4b\u51c6\u786e\u6027\u3002<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u9c8d\u66fc\u4e0d\u52a8\u6746\u83cc\uff08a\uff09\u3001\u5927\u80a0\u6746\u83cc\uff08b\uff09\u548c\u80ba\u708e\u514b\u96f7\u4f2f\u83cc\uff08c\uff09\u7eb3\u7c73\u5b54\u5e8f\u5217\u4e2d\u4ece\u5de6\u81f3\u53f3\u5404\u5b54\u989c\u8272\u5f3a\u5ea6\u7684\u53d8\u5316\uff0c\u901a\u8fc7\u6298\u7ebf\u56fe\u548c\u70ed\u56fe\u5c55\u793a\u3002\u70ed\u56fe\u4e2d\u84dd\u8272\u6846\u6240\u793a\u7684\u7a81\u53d8\u524d\u7684\u5b54\u4ee3\u8868\u76f8\u5e94\u7684\u6700\u4f4e\u6291\u83cc\u6d53\u5ea6\uff08MIC\uff09\u3002\u6bcf\u79cd\u7ec6\u83cc-\u6297\u751f\u7d20\u7ec4\u5408\u5747\u8fdb\u884c\u4e09\u6b21\u91cd\u590d\u8bd5\u9a8c\u3002<\/p>\n\n\n\n

\u5bf9\u4e8e\u8461\u8404\u7403\u83cc\u5c5e\uff08\u5305\u62ec\u91d1\u9ec4\u8272\u8461\u8404\u7403\u83cc\u4e0e\u51dd\u56fa\u9176\u9634\u6027\u8461\u8404\u7403\u83cc\uff09\uff0c\u7cfb\u7edf\u5728 0.19 – 1.5\u03bcg\/mL \u7684\u7a84 MIC \u8303\u56f4\u5185\u4ecd\u80fd\u4fdd\u6301\u9ad8\u7cbe\u5ea6\uff0c16 \u682a\u5df2\u77e5 MIC \u7684\u83cc\u682a\u6d4b\u8bd5\u4e2d\u672c\u8d28\u4e00\u81f4\u6027\uff08EA\uff09\u8fbe\u5230 100%\u3002\u5176\u4e2d\uff0c\u6eb6\u8840\u8461\u8404\u7403\u83cc 901622 – 2 \u682a\u7684 SDFAST \u68c0\u6d4b\u503c\u4e3a 1.56\u03bcg\/mL\uff0c\u4e0e E – test \u7ed3\u679c 1.5\u03bcg\/mL \u9ad8\u5ea6\u543b\u5408\uff0c\u8868\u660e\u5176\u5bf9\u9769\u5170\u6c0f\u9633\u6027\u83cc\u540c\u6837\u5177\u6709\u51fa\u8272\u7684\u5206\u8fa8\u80fd\u529b\u3002<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u7247\u4e0a\u89c2\u5bdf\u5230\u768416\u79cd\u8461\u8404\u7403\u83cc\u523a\u6fc0WST-8\u989c\u8272\u6a21\u5f0f\u7684\u70ed\u56fe\u3002\u6bcf\u79cd\u8461\u8404\u7403\u83cc – \u4e07\u53e4\u9709\u7d20\u7ec4\u5408\u5747\u8fdb\u884c\u4e09\u6b21\u91cd\u590d\u6d4b\u8bd5\u3002<\/p>\n\n\n\n

2)    \u4e34\u5e8a\u6837\u672c\u9a8c\u8bc1<\/h3>\n\n\n\n

\u5728 51 \u682a\u4e34\u5e8a\u5206\u79bb\u83cc\u7684\u6d4b\u8bd5\u4e2d\uff0c\u7cfb\u7edf\u603b\u4f53\u672c\u8d28\u4e00\u81f4\u6027\u8fbe\u5230 92%\uff0c\u6db5\u76d6\u8461\u8404\u7403\u83cc\u5c5e\uff08MRSA\u3001MRCNS \u7b49\uff09\u3001\u80a0\u7403\u83cc\u5c5e\uff08VRE \u7b49\uff09\u53ca Nostoc \u5c5e\u7b49\u591a\u79cd\u5fae\u751f\u7269\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c62.7% \u7684\u6837\u672c\u68c0\u6d4b\u503c\u7565\u4f4e\u4e8e E – test \u7ed3\u679c\uff0c\u8fd9\u4e0e E – test \u5b9e\u9645\u64cd\u4f5c\u4e2d\u503e\u5411\u4e8e\u8bfb\u53d6\u692d\u5706\u6291\u83cc\u5708\u4e0a\u65b9\u6570\u503c\u7684\u4e60\u60ef\u6709\u5173\uff0c\u800c SDFAST \u57fa\u4e8e\u989c\u8272\u53d8\u5316\u7684\u5ba2\u89c2\u5224\u65ad\u66f4\u63a5\u8fd1\u771f\u5b9e\u6291\u83cc\u6d53\u5ea6\u3002\u8fd9\u79cd\u5dee\u5f02\u8fdb\u4e00\u6b65\u51f8\u663e\u4e86\u5fae\u6d41\u63a7\u68c0\u6d4b\u5728\u6807\u51c6\u5316\u65b9\u9762\u7684\u4f18\u52bf\u3002<\/p>\n\n\n\n

4.    \u5fae\u6d41\u4f53\u82af\u7247\u6280\u672f\u7684\u4f18\u52bf\u4e0e\u672a\u6765\u5c55\u671b<\/h2>\n\n\n\n

1)    \u76f8\u6bd4\u4f20\u7edf\u65b9\u6cd5\u7684\u7a81\u7834<\/h3>\n\n\n\n

\u4e0e\u743c\u8102\u6269\u6563\u6cd5\u3001\u8089\u6c64\u7a00\u91ca\u6cd5\u7b49\u4f20\u7edf AST \u6280\u672f\u76f8\u6bd4\uff0cSDFAST \u7cfb\u7edf\u5c06\u68c0\u6d4b\u65f6\u95f4\u4ece 16 – 24 \u5c0f\u65f6\u7f29\u77ed\u81f3 4 – 6 \u5c0f\u65f6\uff0c\u4e14\u6837\u672c\u6d88\u8017\u91cf\u663e\u8457\u964d\u4f4e\uff0c\u6bcf\u901a\u9053\u4ec5\u9700 10 – 20\u03bcL \u6eb6\u6db2\u3002\u5176\u989c\u8272 imetric \u68c0\u6d4b\u6a21\u5f0f\u65e0\u9700\u4f9d\u8d56\u5206\u5149\u5149\u5ea6\u8ba1\u7b49\u5927\u578b\u8bbe\u5907\uff0c\u7ed3\u5408\u667a\u80fd\u624b\u673a\u6210\u50cf\u4e0e\u6df1\u5ea6\u5b66\u4e60\u7b97\u6cd5\u53ef\u5b9e\u73b0\u73b0\u573a\u5feb\u901f\u5224\u8bfb\uff0c\u5b8c\u7f8e\u5951\u5408 point – of – care testing\uff08POCT\uff09\u7684\u5e94\u7528\u573a\u666f\u3002\u5728\u64cd\u4f5c\u7b80\u4fbf\u6027\u4e0a\uff0c\u901a\u8fc7 Clip \u56fa\u5b9a\u4e0e\u5355\u6b21\u6ed1\u52a8\u5373\u53ef\u5b8c\u6210\u7a00\u91ca\u4e0e\u6df7\u5408\uff0c\u975e\u4e13\u4e1a\u4eba\u5458\u7ecf\u77ed\u671f\u57f9\u8bad\u5373\u53ef\u638c\u63e1\uff0c\u514b\u670d\u4e86\u4f20\u7edf\u5fae\u6d41\u63a7\u8bbe\u5907\u5bf9\u64cd\u4f5c\u6280\u80fd\u7684\u9ad8\u8981\u6c42\u3002<\/p>\n\n\n\n

2)    \u6280\u672f\u5c40\u9650\u6027\u4e0e\u6539\u8fdb\u65b9\u5411<\/h3>\n\n\n\n

\u5f53\u524d\u7cfb\u7edf\u5b58\u5728\u7684\u4e3b\u8981\u6311\u6218\u5305\u62ec\uff1a\u80a0\u7403\u83cc\u5c5e\u83cc\u682a\u9700\u8981\u66f4\u957f\u5b75\u80b2\u65f6\u95f4\uff0c\u63a8\u6d4b\u4e0e\u5fae\u6db2\u6ef4\u4e2d\u7ec6\u83cc\u751f\u957f\u901f\u7387\u964d\u4f4e\u76f8\u5173\uff1b\u5fae\u578b\u5316\u5bfc\u81f4\u7684\u68c0\u6d4b\u65f6\u95f4\u5ef6\u957f\uff08\u5b8f\u89c2 WST – 8 \u68c0\u6d4b\u4ec5\u9700 2 – 4 \u5c0f\u65f6\uff09\u3002\u672a\u6765\u53ef\u901a\u8fc7\u4ee5\u4e0b\u6539\u8fdb\u7a81\u7834\u74f6\u9888\uff1a\u91c7\u7528\u8679\u5438\u9a71\u52a8\u7684\u65e0\u6cf5\u538b\u529b\u6ce8\u5165\u7cfb\u7edf\u5b9e\u73b0\u81ea\u52a8\u5316\u52a0\u6837\uff1b\u8bbe\u8ba1\u63a8\u5757\u7ed3\u6784\u5b8c\u6210\u82af\u7247\u81ea\u52a8\u6ed1\u52a8\uff1b\u96c6\u6210\u5546\u7528\u6e29\u63a7\u6a21\u5757\u66ff\u4ee3\u4f20\u7edf\u57f9\u517b\u7bb1\uff1b\u5f00\u53d1\u57fa\u4e8e\u667a\u80fd\u624b\u673a\u7684\u5b9e\u65f6\u6210\u50cf\u4e0e MIC \u8ba1\u7b97\u7b97\u6cd5\u3002\u8fd9\u4e9b\u6539\u8fdb\u601d\u8def\u4e0e\u5668\u5b98\u82af\u7247\u52a0\u5de5\u4e2d\u8ffd\u6c42\u7684\u81ea\u52a8\u5316\u3001\u96c6\u6210\u5316\u7406\u5ff5\u9ad8\u5ea6\u4e00\u81f4\u3002<\/p>\n\n\n\n

3)    \u4e0e\u5176\u4ed6\u5fae\u6d41\u63a7\u6280\u672f\u7684\u534f\u540c\u53d1\u5c55<\/h3>\n\n\n\n

SDFAST\u00a0\u7cfb\u7edf\u7684\u81ea\u7a00\u91ca\u7279\u6027\u5f25\u8865\u4e86\u73b0\u6709\u5fae\u6d41\u63a7\u5e73\u53f0\u7684\u4e0d\u8db3\u3002\u76f8\u6bd4\u4f9d\u8d56\u6269\u6563\u7684\u68af\u5ea6\u6db2\u6ef4\u00a0SlipChip\uff08\u9700\u00a024\u00a0\u5c0f\u65f6\u7a00\u91ca\uff09\uff0c\u5176\u79d2\u7ea7\u7a00\u91ca\u901f\u5ea6\u5927\u5e45\u63d0\u5347\u6548\u7387\uff1b\u4e0e\u96c6\u6210\u4ecb\u7535\u6cf3\u7684\u590d\u6742\u7cfb\u7edf\u76f8\u6bd4\uff0c\u7b80\u5316\u4e86\u64cd\u4f5c\u6d41\u7a0b\u3002\u672a\u6765\u53ef\u7ed3\u5408\u00a0MEMS\u00a0\u52a0\u5de5\u4e2d\u7684\u7cbe\u5bc6\u4f20\u611f\u6280\u672f\uff0c\u5f00\u53d1\u591a\u53c2\u6570\u540c\u6b65\u68c0\u6d4b\u82af\u7247\uff1b\u6216\u501f\u9274\u00a03D\u00a0\u7ec6\u80de\u57f9\u517b\u82af\u7247\u7684\u8bbe\u8ba1\u7406\u5ff5\uff0c\u6784\u5efa\u66f4\u63a5\u8fd1\u4f53\u5185\u73af\u5883\u7684\u836f\u654f\u6d4b\u8bd5\u6a21\u578b\uff0c\u8fdb\u4e00\u6b65\u62d3\u5c55\u5176\u5728\u00a0antimicrobial\u00a0resistance\uff08AMR\uff09\u7814\u7a76\u4e2d\u7684\u5e94\u7528\u4ef7\u503c\u3002 \u5fae\u6d41\u4f53\u82af\u7247\u6280\u672f\u6b63\u901a\u8fc7\u4e0d\u65ad\u521b\u65b0\u63a8\u52a8\u6297\u83cc\u836f\u654f\u68c0\u6d4b\u5411\u5feb\u901f\u5316\u3001\u4fbf\u643a\u5316\u3001\u667a\u80fd\u5316\u53d1\u5c55\uff0cSDFAST\u00a0\u7cfb\u7edf\u4f5c\u4e3a\u5176\u4e2d\u7684\u5178\u578b\u4ee3\u8868\uff0c\u5176\u7ed3\u6784\u8bbe\u8ba1\u4e0e\u5e94\u7528\u6a21\u5f0f\u4e3a\u00a0POCT\u00a0\u9886\u57df\u7684\u5fae\u6d41\u63a7\u5668\u4ef6\u5f00\u53d1\u63d0\u4f9b\u4e86\u91cd\u8981\u53c2\u8003\uff0c\u6709\u671b\u5728\u904f\u5236\u6297\u751f\u7d20\u6ee5\u7528\u3001\u5e94\u5bf9\u5168\u7403\u00a0AMR\u00a0\u6311\u6218\u4e2d\u53d1\u6325\u5173\u952e\u4f5c\u7528\u3002<\/p>","protected":false},"excerpt":{"rendered":"

\u5fae\u6d41\u4f53\u82af\u7247\u6280\u672f\u6b63\u901a\u8fc7\u4e0d\u65ad\u521b\u65b0\u63a8\u52a8\u6297\u83cc\u836f\u654f\u68c0\u6d4b\u5411\u5feb\u901f\u5316\u3001\u4fbf\u643a\u5316\u3001\u667a\u80fd\u5316\u53d1\u5c55\uff0cSDFAST \u7cfb\u7edf\u4f5c\u4e3a\u5176\u4e2d\u7684\u5178\u578b\u4ee3\u8868\uff0c\u5176\u7ed3\u6784\u8bbe\u8ba1\u4e0e\u5e94\u7528\u6a21\u5f0f\u4e3a POCT \u9886\u57df\u7684\u5fae\u6d41\u63a7\u5668\u4ef6\u5f00\u53d1\u63d0\u4f9b\u4e86\u91cd\u8981\u53c2\u8003\uff0c\u6709\u671b\u5728\u904f\u5236\u6297\u751f\u7d20\u6ee5\u7528\u3001\u5e94\u5bf9\u5168\u7403 AMR 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