{"id":3957,"date":"2025-04-22T16:30:00","date_gmt":"2025-04-22T08:30:00","guid":{"rendered":"https:\/\/www.dxfluidics.com\/?p=3957"},"modified":"2025-04-22T15:14:37","modified_gmt":"2025-04-22T07:14:37","slug":"%e8%a1%a8%e9%9d%a2%e5%a4%84%e7%90%86%e6%8a%80%e6%9c%af","status":"publish","type":"post","link":"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/3957\/%e8%a1%a8%e9%9d%a2%e5%a4%84%e7%90%86%e6%8a%80%e6%9c%af\/","title":{"rendered":"\u8868\u9762\u5904\u7406\u6280\u672f"},"content":{"rendered":"

\u53c2\u8003\u6587\u732e\uff1aInterfacial engineering for biomolecule immobilisation in microfluidic devices – ScienceDirect<\/a><\/a><\/p>\n\n\n\n

\u672c\u6587\u6982\u62ec\u4e86\u7528\u4e8e\u5fae\u6d41\u4f53\u5668\u4ef6surface modification<\/a>\u7684\u4e0d\u540c\u6280\u672f\uff0c\u8fd9\u4e9b\u6280\u672f\u88ab\u5206\u4e3a\u6c14\u76f8\u5904\u7406\u548c\u6e7f\u5316\u5b66\u5904\u7406\u4e24\u5927\u7c7b\u3002<\/p>\n\n\n\n

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1.    \u5316\u5b66\u6c14\u76f8\u6c89\u79ef\uff08CVD\uff09<\/h2>\n\n\n\n

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\n
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\u5fae\u6d41\u4f53\u5668\u4ef6\u7684 CVD \u6539\u6027<\/figcaption><\/figure>\n<\/div>\n\n\n

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2.    \u7d2b\u5916\u7ebf\/\u81ed\u6c27\u5904\u7406<\/h2>\n\n\n\n

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\n
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\u5fae\u6d41\u4f53\u5668\u4ef6\u7684 UV\/UVO \u6539\u6027<\/figcaption><\/figure>\n<\/div>\n\n\n

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Khetani\u7b49\u5219\u5728PDMS\u5fae\u901a\u9053\u5185\u586b\u5145\u591a\u5df4\u80fa\u548c\u53bb\u7532\u80be\u4e0a\u817a\u7d20\u5355\u4f53\uff0c\u901a\u8fc7\u7d2b\u5916\u5149\u5f15\u53d1\u805a\u5408\u5f62\u6210\u7a33\u5b9a\u6d82\u5c42\uff0c\u4e0e\u672a\u4fee\u9970\u82af\u7247\u76f8\u6bd4\uff0c\u8be5\u6d82\u5c42\u663e\u8457\u63d0\u5347\u4e86CAD\u7ec6\u80de\u7684\u5b58\u6d3b\u3001\u9ecf\u9644\u3001\u589e\u6b96\u53ca\u57fa\u56e0\u8868\u8fbe\u6c34\u5e73\u3002<\/p>\n\n\n\n

3.    \u7b49\u79bb\u5b50\u4f53\u5904\u7406<\/h2>\n\n\n\n

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\n
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Tan\u7b49\u4eba\u53d1\u73b0\uff0cPDMS\u7ecf\u5355\u6b21\u6216\u591a\u6b21\uff08100-500\u79d2\uff09\u7b49\u79bb\u5b50\u4f53\u5904\u7406\u540e\uff0c\u6c34\u63a5\u89e6\u89d2\u964d\u81f317\u00b0\u201346\u00b0\uff08\u4eb2\u6c34\u6027\u663e\u8457\u63d0\u5347\uff09\uff0c\u4e14\u6539\u6027\u6548\u679c\u53ef\u7ef4\u63016\u5c0f\u65f6\uff0c\u6ee1\u8db3\u5546\u4e1a\u5316\u5668\u4ef6\u5236\u9020\u9700\u6c42\u3002<\/p>\n\n\n\n

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4.    \u7845\u70f7\u3001\u78b3\u4e8c\u4e9a\u80fa\u548c\u5e2d\u592b\u78b1\u5316\u5b66<\/h2>\n\n\n\n

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\n
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\u8fd9\u79cd\u589e\u5f3a\u7684\u529b\u5b66\u7a33\u5b9a\u6027\u4f7f\u8be5\u88c5\u7f6e\u9002\u7528\u4e8e\u751f\u7269\u529b\u5b66\u7814\u7a76\uff0c\u4f8b\u5982\u6a21\u62df\u51a0\u72b6\u52a8\u8109\u526a\u5207\u5e94\u529b\u5bf9\u5185\u76ae\u7ec6\u80de\u7684\u5f71\u54cd\u3002<\/p>\n\n\n\n

5.    \u5c42\u5c42\u81ea\u7ec4\u88c5<\/h2>\n\n\n\n

\u5c42\u5c42\u81ea\u7ec4\u88c5\uff08LBL\uff09\u6c89\u79ef\u662f\u901a\u8fc7\u5c06\u5e26\u7535\u57fa\u5e95\u6d78\u5165\u542b\u6709\u76f8\u53cd\u7535\u8377\u7269\u79cd\u7684\u6eb6\u6db2\u4e2d\uff0c\u5e76\u7ecf\u8fc7\u4e2d\u95f4\u51b2\u6d17\u548c\u5e72\u71e5\u6b65\u9aa4\uff0c\u5f62\u6210\u591a\u5c42\u7ed3\u6784\u7684\u8fc7\u7a0b\u3002<\/p>\n\n\n\n

\u6bcf\u6b21\u6d78\u6e0d\u6b65\u9aa4\u5305\u62ec\u4ece\u6d78\u6e0d\u6eb6\u6db2\u4e2d\u6c89\u79ef\u4e00\u5c42\u5e26\u7535\u7269\u8d28\uff0c\u5e76\u53cd\u8f6c\u8868\u9762\u7535\u8377\uff0c\u4ece\u800c\u4f7f\u4e0b\u4e00\u5c42\u76f8\u53cd\u7535\u8377\u7684\u7269\u8d28\u6c89\u79ef\u3002<\/p>\n\n\n\n

\u901a\u8fc7\u8c03\u6574\u7ec4\u88c5\u53c2\u6570\uff0c\u5982\u6d78\u6e0d\u6eb6\u6db2\u7684\u79bb\u5b50\u5f3a\u5ea6\u3001\u7ec4\u6210\u3001\u6e29\u5ea6\u548cpH\u503c\uff0c\u53ef\u4ee5\u63a7\u5236\u6d82\u5c42\u7279\u6027\uff0c\u5982\u5c42\u7ec4\u6210\u3001\u5730\u5f62\u3001\u539a\u5ea6\u4ee5\u53ca\u76f8\u90bb\u5c42\u4e4b\u95f4\u7684\u6df7\u5408\u7a0b\u5ea6\u3002<\/p>\n\n\n

\n
\"\"
\u57fa\u4e8e LBL \u7684\u5fae\u6d41\u4f53\u8868\u9762\u6539\u6027<\/figcaption><\/figure>\n<\/div>\n\n\n

Lin\u7b49\u5f00\u53d1\u4e86\u4e00\u79cd\u53cc\u5c42organ chip<\/a>\uff0c\u901a\u8fc7\u96c6\u6210\u7ec6\u80de\u57f9\u517b\u5fae\u901a\u9053\uff0840\u00d71\u00d70.05 mm\uff09\u548c\u751f\u7269\u4f20\u611f\u5fae\u6c9f\u69fd\uff08500\u00d7100\u00d7200 \u03bcm\uff09\uff0c\u5b9e\u73b0\u4e86\u7ec6\u80de\u5f62\u6001\u76d1\u6d4b\u4e0e\u8461\u8404\u7cd6\/\u6c27\u6c14\u6d53\u5ea6\u7684\u540c\u6b65\u68c0\u6d4b\uff0c\u5176\u57fa\u8d28\u8f85\u52a9LBL\u5c01\u88c5\u6280\u672f\u4e3adrug screening<\/a>\u63d0\u4f9b\u4e86\u65b0\u5e73\u53f0\u3002<\/p>\n\n\n\n

Li\u7b49\u5219\u91c7\u7528LBL\u6280\u672f\u5728\u5fae\u6d41\u63a7\u901a\u9053\u6784\u5efa\u4e8614 nm\u539a\u7684\u4e94\u5c42CNF\u53ef\u964d\u89e3\u6d82\u5c42\uff0c\u901a\u8fc7\u9176\u89e3\u5b9e\u73b0CTCs\u7684\u9ad8\u6548\u6355\u83b7\u4e0e\u65e0\u635f\u91ca\u653e\uff0c\u5728\u4fdd\u6301\u7ec6\u80de\u6d3b\u6027\u548c\u589e\u6b96\u80fd\u529b\u7684\u540c\u65f6\u5c55\u73b0\u4e86\u4f18\u5f02\u7684\u5faa\u73af\u80bf\u7624\u7ec6\u80de\u5206\u9009<\/a>\u6027\u80fd\u3002<\/p>\n\n\n\n

6.    \u5176\u4ed6\u8868\u9762\u5904\u7406\u6280\u672f<\/h2>\n\n\n\n

\u7535\u7eba\u4e1d\u662f\u4e00\u79cd\u5229\u7528\u7535\u573a\u4ece\u805a\u5408\u7269\u6eb6\u6db2\u4e2d\u5236\u5907\u7eb3\u7c73\u7ea4\u7ef4\u7684\u6280\u672f\u3002<\/p>\n\n\n\n

\u5728\u6b64\u8fc7\u7a0b\u4e2d\uff0c\u805a\u5408\u7269\u6eb6\u6db2\u88ab\u6ce8\u5165\u6ce8\u5c04\u5668\u5e76\u5e26\u6b63\u7535\u8377\uff0c\u968f\u540e\u4ee5\u6700\u4f73\u6d41\u901f\u6cf5\u51fa\u5e76\u6c89\u79ef\u5728\u5e26\u76f8\u53cd\u7535\u8377\u7684\u6536\u96c6\u677f\u4e0a\u3002<\/p>\n\n\n\n

\u7535\u7eba\u4e1d\u6280\u672f\u88ab\u7528\u4e8e\u5236\u5907\u805a\u4e73\u9178-\u5171-\u4e59\u9187\u9178\uff08PLGA\uff09\u57fa\u7eb3\u7c73\u7ea4\u7ef4\u754c\u9762\uff0c\u4ee5\u5728\u5fae\u6d41\u4f53\u82af\u7247\u4e2d\u9ad8\u6548\u6355\u83b7\u5faa\u73af\u80bf\u7624\u7ec6\u80de\uff08CTCs\uff09\u3002<\/p>\n\n\n\n

\u7ea4\u7ef4\u88ab\u7eba\u5236\u5728\u73bb\u7483\u76d6\u7247\u4e0a\uff0c\u5e76\u901a\u8fc7PMMA\u6216PDMS\u4e0e\u5177\u6709\u8154\u4f53\u7684\u57fa\u5e95\u7ed3\u5408\u3002<\/p>\n\n\n\n

\u7ea4\u7ef4\u8868\u9762\u901a\u8fc7\u5171\u4ef7\u952e\u56fa\u5b9a\u4e0a\u4e0a\u76ae\u7ec6\u80de\u7c98\u9644\u5206\u5b50\uff08EpCAM\uff09\u6297\u4f53\u6216\u900f\u660e\u8d28\u9178\uff08HA\uff09\uff0c\u4ee5\u63d0\u9ad8\u80bf\u7624\u7ec6\u80de\u7684\u6355\u83b7\u6548\u7387\u3002<\/p>\n\n\n

\n
\"\"
\u5fae\u6d41\u4f53\u88c5\u7f6e\u7684\u9759\u7535\u7eba\u4e1d\u6539\u6027<\/figcaption><\/figure>\n<\/div>\n\n\n

Rhyou\u7b49\u6210\u529f\u5728PDMS\u5fae\u6d41\u63a7\u82af\u7247\u4e2d\u96c6\u6210\u7535\u7eba\u805a\u5df1\u5185\u916f\u819c\uff0c\u5b9e\u73b07\u5929\u6d41\u5f0f\u57f9\u517b\u4e0b\u4eba\u7c7b\u89d2\u8d28\u5f62\u6210\u7ec6\u80de95%\u7684\u9ad8\u5b58\u6d3b\u7387\uff0c\u8be5\u7535\u7eba\u754c\u9762\u7ecf\u5316\u5b66\u6d3b\u5316\u540e\u53ef\u5171\u4ef7\u56fa\u5b9a\u751f\u7269\u5206\u5b50\u3002<\/p>\n\n\n\n

Kim\u56e2\u961f\u5219\u521b\u65b0\u6027\u5730\u5229\u7528\u56fe\u6848\u5316PDMS\u5fae\u901a\u9053\u7ed3\u5408\u6eb6\u80f6-\u51dd\u80f6\u6280\u672f\uff0c\u5728\u4eb2\u6c34\u5316\u5904\u7406\u7684\u73bb\u7483\u57fa\u5e95\u4e0a\u6784\u5efa\u4e86\u5177\u6709\u6d3b\u6027IgG\u7684\u5fae\u56fe\u6848\uff0c\u901a\u8fc7\u514d\u75ab\u7ed3\u5408\u5b9e\u9a8c\u8bc1\u5b9e\u4e86\u86cb\u767d\u8d28\u529f\u80fd\u7684\u5b8c\u6574\u4fdd\u7559\uff0c\u4e3a\u86cb\u767d\u8d28\u82af\u7247\u5f00\u53d1\u63d0\u4f9b\u4e86\u65b0\u7b56\u7565\u3002<\/p>","protected":false},"excerpt":{"rendered":"

\u53c2\u8003\u6587\u732e\uff1aInterfacial engineering for biomolecule immobilisa […]<\/p>\n","protected":false},"author":2,"featured_media":3964,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","footnotes":""},"categories":[5],"tags":[],"class_list":["post-3957","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-information"],"yoast_head":"\n\u8868\u9762\u5904\u7406\u6280\u672f - \u9876\u65ed\u5fae\u63a7<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/3957\/\u8868\u9762\u5904\u7406\u6280\u672f\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u8868\u9762\u5904\u7406\u6280\u672f - \u9876\u65ed\u5fae\u63a7\" \/>\n<meta property=\"og:description\" content=\"\u53c2\u8003\u6587\u732e\uff1aInterfacial engineering for biomolecule immobilisa […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/3957\/\u8868\u9762\u5904\u7406\u6280\u672f\/\" \/>\n<meta property=\"og:site_name\" content=\"\u9876\u65ed\u5fae\u63a7\" \/>\n<meta property=\"article:published_time\" content=\"2025-04-22T08:30:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.dxfluidics.com\/wp-content\/uploads\/2025\/04\/VCG41N1054729198.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"533\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"dxfluidics\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" 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