{"id":2344,"date":"2024-06-18T17:28:43","date_gmt":"2024-06-18T09:28:43","guid":{"rendered":"https:\/\/www.dxfluidics.com\/?p=2344"},"modified":"2024-09-14T13:09:06","modified_gmt":"2024-09-14T05:09:06","slug":"%e5%be%ae%e6%b5%81%e6%8e%a7%e8%8a%af%e7%89%87%e7%a7%8d%e7%b1%bb","status":"publish","type":"post","link":"https:\/\/www.dxfluidics.com\/en\/technical-support\/information\/2344\/%e5%be%ae%e6%b5%81%e6%8e%a7%e8%8a%af%e7%89%87%e7%a7%8d%e7%b1%bb\/","title":{"rendered":"Common Materials and Properties of Microfluidic Chips"},"content":{"rendered":"

Microfluidic chip is based on the development of microelectromechanical systems (MEMS), through the microfabrication technology of microchannels, microvalves<\/a>, micro-pumps<\/a> and microelectrodes and other different functions of the micro-components are integrated together to constitute the micro-analytical system.<\/p>\n\n\n\n

As the carrier of the microfluidic chip, the chip material determines the processing difficulty, precision, functionality, and cost of the chip, and the selection of the chip material generally takes into account its chemical and biocompatibility, electrical insulation, heat dissipation, modifiability, optical properties, material and processing costs, etc. The chip material can be used in a wide range of applications, including microfluidic chips, microfluidic chips, and microfluidic chips.<\/p>\n\n\n\n

The choice of material for microfluidic chip fabrication is a key determinant. Initially, silicon material dominated the microfluidic chip preparation due to its superior properties, but with the diversification of the application scenarios, the limitations of silicon material are gradually revealed, especially its defects of not being able to withstand high voltage and not being compatible with optical detection technology.<\/p>\n\n\n\n

To overcome these problems, the industry and research community have begun to explore new material options. Glass is theoretically well suited for the fabrication of microfluidic chips due to its excellent electroosmotic and optical properties, however, its complex fabrication process, expensive cost, and difficulty in photolithography and etching limit its large-scale application.<\/p>\n\n\n\n

Compared with this, polymer materials show obvious advantages. Polymer production process is simple, the cost of raw materials is low, at the same time has good insulation, high voltage resistance, thermal stability, biocompatibility, gas permeability and low elastic modulus and other characteristics. These properties make them widely used in capillary electrophoresis microchips, biochemical reaction chips, and a variety of optical detection systems.<\/p>\n\n\n\n

At present, organic polymers represented by polydimethylsiloxane (PDMS) have become one of the mainstream materials for microfluidic chip fabrication, and their excellent performance and relatively simple fabrication process have made them widely popular.<\/p>\n\n\n\n

Commonly used materials for microfluidic chips and their properties<\/td><\/tr>
Performance indicators<\/td>galss<\/td>PDMS<\/td>PMMA<\/td>PC<\/td>paper base<\/td><\/tr>
biocompatibility<\/td>comparatively good<\/td>susceptible to non-specific adsorption<\/td>comparatively good<\/td>comparatively good<\/td>comparatively good<\/td><\/tr>
Optical properties<\/td>comparatively good<\/td>comparatively good<\/td>comparatively good<\/td>Poor UV absorption<\/td>Low detection background<\/td><\/tr>
thermal conductivity<\/td>comparatively good<\/td>low<\/td>low<\/td>low<\/td>low<\/td><\/tr>
electrical insulation<\/td>comparatively good<\/td>comparatively good<\/td>comparatively good<\/td>comparatively good<\/td>comparatively good<\/td><\/tr>
thermal stability<\/td>\uff0d\uff18\uff10\uff5e\uff18\uff16\uff10\u2103<\/td>\uff0d\uff15\uff10\uff5e\uff12\uff10\uff10\u2103<\/td>\uff0d\uff18\uff10\uff5e\uff19\uff10\u2103<\/td>\uff0d\uff16\uff10\uff5e\uff11\uff12\uff10\u2103<\/td>Easily evaporated by heat<\/td><\/tr>
Cost of materials<\/td>Moderate<\/td>Moderate<\/td>Moderate<\/td>Moderate<\/td>low<\/td><\/tr>
processing difficulty<\/td>relatively difficult<\/td>Moderate<\/td>Moderate<\/td>Moderate<\/td>easy<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

silicon<\/h2>\n\n\n\n

vantage<\/h3>\n\n\n\n